Evidence map›Paper›PMID 21761152›Full record

ReviewMycopathologia2011

A case of rhinoorbital mucormycosis in a leukemic patient with a literature review from Turkey.

Ramazan Gumral, Uzeyir Yildizoglu, Mehmet Ali Saracli, Kursat Kaptan, Fuat Tosun, Sinasi Taner Yildiran

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Mycopathologia, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Update on invasive fungal infections in the Middle Eastern and North African region.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020
    Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ramazan GumralDepartment of Microbiology, Gulhane Military Medical Academy, Ankara, Turkey, rgumral@gmail.com.
Uzeyir Yildizoglu
Mehmet Ali Saracli
Kursat Kaptan
Fuat Tosun
Sinasi Taner Yildiran
Turkish Armed Forces · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucormycosis (Zygomycosis) is a rare, invasive, opportunistic fungal infection of the paranasal sinuses, caused by a fungus of the order Mucorales. We report a case of rhinoorbital mucormycosis caused by Rhizopus oryzae in an acute lymphoblastic leukemia patient and review the 79 Mucormycosis cases reported in the last decade from Turkey. In our case, the diagnosis was made with endoscopic appearance, computerized tomography of the paranasal sinuses, and culture of the surgical materials. Following aggressive surgical debridement and parenteral amphotericin B therapy, the patient recovered completely. In Turkish literature, rhinocerebral manifestations were the most common form of the mucormycosis (64 cases), followed by pulmonary form (6 cases). The most common risk factor was hematologic malignancies (32 cases) and diabetes mellitus (32 cases), similar to those reported from the rest of the world. The etiologic agents responsible for the review cases were Rhizopus sp., Mucor spp., Rhizomucor spp., Rhizopus oryzae, Mucor circinelloides, and Lichtheimia corymbifera. Although various treatment modalities were used, amphotericin B was the mainstay of therapy. Mortality rate was found to be 49.4% in review cases. It seems that strong clinical suspicion and early diagnosis, along with aggressive antifungal therapy and endoscopic sinus surgery, have great importance for better prognosis in mucormycosis.

Indexed as

MucormycosisParanasal Sinus DiseasesRhizopusAdultAmphotericin BAntifungal AgentsBase SequenceDNA, FungalHumansMaleParanasal SinusesPrecursor Cell Lymphoblastic Leukemia-LymphomaRNA, Ribosomal, 5.8SSequence Analysis, DNATurkeyAmphotericin BAntifungal AgentsDNA, Fungalliposomal amphotericin BRNA, Ribosomal, 5.8S

Identifiers

PMID21761152
OpenAlexW2012105984

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.