ArticleInternational journal of Alzheimer's disease2011
Joint assessment of structural, perfusion, and diffusion MRI in Alzheimer's disease and frontotemporal dementia.
Article in International journal of Alzheimer's disease, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
49 citing papers in PubMed, 80 citations in OpenAlex.
- Cognitive reserve and longitudinal changes in brain and cognition in semantic variant primary progressive aphasia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Artificial intelligence-based speech error detection to differentiate primary progressive aphasia variants.Brain communications · 2026Article
- Automated Speech Analysis to Differentiate Frontal and Right Anterior Temporal Lobe Atrophy in Frontotemporal Dementia.Neurology · 2025Article
- Diabetes-related cognitive impairment: Mechanisms, symptoms, and treatments.Open medicine (Warsaw, Poland) · 2025Review
- Pathology-specific patterns of cerebellar atrophy in neurodegenerative disorders.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Pathologic burden goes with the flow: MRI perfusion and pathologic burden in frontotemporal lobar degeneration due to tau.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Neurofilament light levels predict clinical progression and death in multiple system atrophy.Brain : a journal of neurology · 2022Article
- Arterial spin labeling demonstrates preserved regional cerebral blood flow in the P301L mouse model of tauopathy.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Article
- Differences in Multimodal Electroencephalogram and Clinical Correlations Between Early-Onset Alzheimer's Disease and Frontotemporal Dementia.Frontiers in neuroscience · 2021Article
- An update on magnetic resonance imaging markers in AD.Therapeutic advances in neurological disorders · 2020Review
- Classification using fractional anisotropy predicts conversion in genetic frontotemporal dementia, a proof of concept.Brain communications · 2020Article
- Multimodal MRI of grey matter, white matter, and functional connectivity in cognitively healthy mutation carriers at risk for frontotemporal dementia and Alzheimer's disease.BMC neurology · 2019Article
- Article
- Primary progressive aphasia and the FTD-MND spectrum disorders: clinical, pathological, and neuroimaging correlates.Amyotrophic lateral sclerosis & frontotemporal degeneration · 2019Article
- An update on advances in magnetic resonance imaging of multiple system atrophy.Journal of neurology · 2019Review
- Neuroimaging in aging and neurologic diseases.Handbook of clinical neurology · 2019Review
- Longitudinal multimodal MRI as prognostic and diagnostic biomarker in presymptomatic familial frontotemporal dementia.Brain : a journal of neurology · 2019Article
- Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia.JAMA neurology · 2018Article
- Single-subject classification of presymptomatic frontotemporal dementia mutation carriers using multimodal MRI.NeuroImage. Clinical · 2018Article
- Using simultaneous PET/MRI to compare the accuracy of diagnosing frontotemporal dementia by arterial spin labelling MRI and FDG-PET.NeuroImage. Clinical · 2018Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
Most MRI studies of Alzheimer's disease (AD) and frontotemporal dementia (FTD) have assessed structural, perfusion and diffusion abnormalities separately while ignoring the relationships across imaging modalities. This paper aimed to assess brain gray (GM) and white matter (WM) abnormalities jointly to elucidate differences in abnormal MRI patterns between the diseases. Twenty AD, 20 FTD patients, and 21 healthy control subjects were imaged using a 4 Tesla MRI. GM loss and GM hypoperfusion were measured using high-resolution T1 and arterial spin labeling MRI (ASL-MRI). WM degradation was measured with diffusion tensor imaging (DTI). Using a new analytical approach, the study found greater WM degenerations in FTD than AD at mild abnormality levels. Furthermore, the GM loss and WM degeneration exceeded the reduced perfusion in FTD whereas, in AD, structural and functional damages were similar. Joint assessments of multimodal MRI have potential value to provide new imaging markers for improved differential diagnoses between FTD and AD.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.