ReviewBiochimica et biophysica acta2011
Glycerolipid and cholesterol ester analyses in biological samples by mass spectrometry.
Review in Biochimica et biophysica acta, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 58 citations in OpenAlex.
- Liquid chromatography-dielectric barrier discharge ionization mass spectrometry for the analysis of neutral lipids of archaeological interest.Journal of separation science · 2022Article
- Article
- A large-scale genome-lipid association map guides lipid identification.Nature metabolism · 2020Article
- Moose and Caribou as Novel Sources of Functional Lipids: Fatty Acid Esters of Hydroxy Fatty Acids, Diglycerides and Monoacetyldiglycerides.Molecules (Basel, Switzerland) · 2019Article
- Mass spectrometry-based shotgun lipidomics - a critical review from the technical point of view.Analytical and bioanalytical chemistry · 2018Review
- Article
- Uncovering Structural Diversity of Unsaturated Fatty Acyls in Cholesteryl Esters via Photochemical Reaction and Tandem Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2017Article
- Extraction, chromatographic and mass spectrometric methods for lipid analysis.Biomedical chromatography : BMC · 2016Review
- Differential sensing for the regio- and stereoselective identification and quantitation of glycerides.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Oxidative lipidomics coming of age: advances in analysis of oxidized phospholipids in physiology and pathology.Antioxidants & redox signaling · 2015Review
- Lipidomic profiling of sinus mucosa from patients with chronic rhinosinusitis.Clinical and translational science · 2015Article
- Lipidomic profiling of mastoid bone and tissue from patients with chronic otomastoiditis.International archives of otorhinolaryngology · 2015Article
- Review
- Bioinformatics: the next frontier of metabolomics.Analytical chemistry · 2015Review
- Article
- Enhanced lipid isomer separation in human plasma using reversed-phase UPLC with ion-mobility/high-resolution MS detection.Journal of lipid research · 2014Article
- Sum of the parts: mass spectrometry-based metabolomics.Biochemistry · 2013Review
- Review
- Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectations.Chemistry and physics of lipids · 2012Review
- Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Neutral lipids are a diverse family of hydrophobic biomolecules that have important roles in cellular biochemistry of all living species but have in common the property of charge neutrality. A large component of neutral lipids is the glycerolipids composed of triacylglycerols, diacylglycerols, and monoacylglycerols that can serve as cellular energy stores as well as signaling molecules. Another abundant lipid class in many cells is the cholesterol esters that are on one hand sterols and the other fatty acyl lipids, but in either case are neutral lipids involved in cholesterol homeostasis and transport in the blood. The analysis of these molecules in the context of lipidomics remains challenging because of their charge neutrality and the complex mixtures of molecular species present in cells. Various techniques have been used to ionize these neutral lipids prior to mass spectrometric analysis including electron ionization, atmospheric chemical ionization, electrospray ionization and matrix assisted laser desorption/ionization. Various approaches to deal with the complex mixture of molecular species have been developed including shotgun lipidomics and chromatographic-based separations such as gas chromatography, reversed phase liquid chromatography, and normal phase liquid chromatography. Several applications of these approaches are discussed. .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.