ArticleSao Paulo medical journal = Revista paulista de medicina2011
Incidence and cost estimate of treating pediatric adverse drug reactions in Lagos, Nigeria.
Article in Sao Paulo medical journal = Revista paulista de medicina, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 6 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Adverse Drug Reaction Costs and Study Quality in Africa: A Systematic Review of Cost-of-Illness Studies.PharmacoEconomics - open · 2026Pooled it
- Variation of adverse drug events in different settings in Africa: a systematic review.European journal of medical research · 2024Pooled it
- The epidemiology of drug-related hospital admissions in paediatrics - a systematic review.Archives of public health = Archives belges de sante publique · 2024Pooled it
- Serious adverse drug reactions in sub-Saharan Africa in the era of antiretroviral treatment: A systematic review.Pharmacology research & perspectives · 2021Pooled it
- Mortality among patients due to adverse drug reactions that occur following hospitalisation: a meta-analysis.European journal of clinical pharmacology · 2019Pooled it
- Mortality among patients due to adverse drug reactions that lead to hospitalization: a meta-analysis.European journal of clinical pharmacology · 2018Pooled it
- Lymphocyte transformation test in pediatric drug hypersensitivity: case series report from a tertiary care hospital.Frontiers in immunology · 2026Article
- Effects of children's criteria for identifying potentially inappropriate prescribing on prescription review by pharmacists: a before-after study.International journal of clinical pharmacy · 2025Article
- Educational intervention impact assessment on pharmacovigilance knowledge, attitude and practice among hospital pharmacy practitioners in Dubai.Journal of pharmaceutical policy and practice · 2025Article
- Identifying strategies to improve adverse drug reporting through key informant interviews among community pharmacists in a developing country.Scientific reports · 2024Article
- Medication-Related Hospital Admission Among Patients Admitted to the Emergency Ward at the University of Gondar, North West Ethiopia: A Cross Sectional Study.Drug, healthcare and patient safety · 2024Article
- Medication errors and associated factors among pediatric inpatients in public hospitals of gamo zone, southern Ethiopia.Heliyon · 2023Article
- Adverse Drug Reactions to Antiretroviral Therapy: Frequency, Type, and Risk Factors in Children in Mali.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2023Article
- Assessment of Knowledge, Attitude and Practice of Adverse Drug Reaction Reporting Among Healthcare Professionals working in Primary, Secondary and Tertiary Healthcare Facilities in Ekiti State, South-West Nigeria.Hospital pharmacy · 2021Article
- Expert Consensus on a List of Inappropriate Prescribing after Prescription Review in Pediatric Units in Abidjan, Côte d'Ivoire.Integrated pharmacy research & practice · 2021Article
- Evaluation of Adverse Drug Reactions in Paediatric Patients: A Retrospective Study in Turkish Hospital.Frontiers in pharmacology · 2021Article
- Adverse drug reactions reporting practice and associated factors among community health extension workers in public health facilities, Southwest, Nigeria.The Pan African medical journal · 2021Article
- Serious adverse drug reactions at two children's hospitals in South Africa.BMC pediatrics · 2020Article
- Severe cutaneous adverse drug reactions manifesting as Stevens-Johnson syndrome and toxic epidermal necrolysis reported to the national pharmacovigilance center in Nigeria: a database review from 2004 to 2017.Therapeutic advances in drug safety · 2020Article
- Descriptive study of adverse drug reactions in a tertiary care pediatric hospital in México from 2014 to 2017.PloS one · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
CONTEXT AND
objectivesAdverse drug reactions (ADRs) may cause prolonged hospital admissions with high treatment costs. The burden of ADRs in children has never been evaluated in Nigeria. The incidence of pediatric ADRs and the estimated cost of treatment over an 18-month period were determined in this study. DESIGN AND
settingProspective observational study on children admitted to the pediatric wards of the Lagos State University Teaching Hospital (LASUTH) in Nigeria, between July 2006 and December 2007.
methodsEach patient was assessed for ADRs throughout admission. Medical and non-medical costs to the hospital and patient were estimated for each ADR by reviewing the medical and pharmacy bills, medical charts and diagnostic request forms and by interviewing the parents. Cost estimates were performed in 2007 naira (Nigeria currency) from the perspectives of the hospital (government), service users (patients) and society (bearers of the total costs attributable to treating ADRs). The total estimated cost was expressed in 2007 United States dollars (USD).
resultsTwo thousand and four children were admitted during the study; 12 (0.6%) were admitted because of ADRs and 23 (1.2%) developed ADR(s) during admission. Forty ADRs were suspected in these 35 patients and involved 53 medicines. Antibiotics (50%) were the most suspected medicines. Approximately 1.83 million naira (USD 15,466.60) was expended to manage all the patients admitted due to ADRs.
conclusionsTreating pediatric ADRs was very expensive. Pediatric drug use policies in Nigeria need to be reviewed so as to discourage self-medication, polypharmacy prescription and sales of prescription medicines without prescription.
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