ArticleMolecular & general genetics : MGG1990
HSP12, a new small heat shock gene of Saccharomyces cerevisiae: analysis of structure, regulation and function.
Article in Molecular & general genetics : MGG, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed.
- Article
- Insight into the biochemical and cell biological function of an intrinsically unstructured heat shock protein, Hsp12 of Ustilago maydis.Molecular plant pathology · 2023Article
- Article
- Enabling growth-decoupledFrontiers in bioengineering and biotechnology · 2023Article
- Article
- Misactivation of multiple starvation responses in yeast by loss of tRNA modifications.Nucleic acids research · 2020Article
- Small but mighty: a functional look at bacterial sHSPs.Cell stress & chaperones · 2020Review
- The InsPThe Journal of biological chemistry · 2020Article
- A class I cytosolic HSP20 of rice enhances heat and salt tolerance in different organisms.Scientific reports · 2020Article
- Spt6 Is Required for the Fidelity of Promoter Selection.Molecular cell · 2018Article
- Article
- Condition-specific promoter activities in Saccharomyces cerevisiae.Microbial cell factories · 2018Article
- The CsHSP17.2 molecular chaperone is essential for thermotolerance in Camellia sinensis.Scientific reports · 2017Article
- The widespread occurrence of tRNA-derived fragments inFEBS open bio · 2016Article
- Quantitative proteomic comparison of stationary/G0 phase cells and tetrads in budding yeast.Scientific reports · 2016Article
- Oxygen availability strongly affects chronological lifespan and thermotolerance in batch cultures ofMicrobial cell (Graz, Austria) · 2015Article
- Solution NMR studies on the orientation of membrane-bound peptides and proteins by paramagnetic probes.Molecules (Basel, Switzerland) · 2013Review
- Distinct and redundant roles of the two MYST histone acetyltransferases Esa1 and Sas2 in cell growth and morphogenesis of Candida albicans.Eukaryotic cell · 2013Article
- Comparative proteomic analysis of transition of saccharomyces cerevisiae from glucose-deficient medium to glucose-rich medium.Proteome science · 2012Article
- System-wide perturbation analysis with nearly complete coverage of the yeast proteome by single-shot ultra HPLC runs on a bench top Orbitrap.Molecular & cellular proteomics : MCP · 2012Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have isolated a new small heat shock gene, HSP12, from Saccharomyces cerevisiae. It encodes a polypeptide of predicted Mr 12 kDa, with structural similarity to other small heat shock proteins. HSP12 gene expression is induced several hundred-fold by heat shock and on entry into stationary phase. HSP12 mRNA is undetectable during exponential growth in rich medium, but low levels are present when cells are grown in minimal medium. Analysis of HSP12 expression in mutants affected in cAMP-dependent protein phosphorylation suggests that the gene is regulated by cAMP as well as heat shock. A disruption of the HSP12 coding region results in the loss of an abundant 14.4 kDa protein present in heat shocked and stationary phase cells. It also leads to the induction of the heat shock response under conditions normally associated with low-level HSP12 expression. The HSP12 disruption has no observable effect on growth at various temperatures, nor on the ability to acquire thermotolerance.
Indexed as
Identifiers
2175390What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.