ArticlePlant physiology2011
Ectopic expression of AtJMT in Nicotiana attenuata: creating a metabolic sink has tissue-specific consequences for the jasmonate metabolic network and silences downstream gene expression.
Article in Plant physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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35 citing papers in PubMed, 78 citations in OpenAlex.
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- Robustness in jasmonate signaling: mechanisms of concerted regulation and implications for crop improvement.aBIOTECH · 2025Review
- Transcription factor ABF3 modulates salinity stress-enhanced jasmonate signaling inPlant diversity · 2024Article
- Integrative Metabolomic and Transcriptomic Analysis Elucidates That the Mechanism of Phytohormones Regulates Floral Bud Development in Alfalfa.Plants (Basel, Switzerland) · 2024Article
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- Triple-localized WHIRLY2 Influences Leaf Senescence and Silique Development via Carbon Allocation.Plant physiology · 2020Article
- Argonaute4 Modulates Resistance toPlant physiology · 2020Article
- Methyl Jasmonate Affects Photosynthesis Efficiency, Expression ofInternational journal of molecular sciences · 2020Article
- Silencing JA hydroxylases inPlant diversity · 2020Article
- Distinct Signatures of Host Defense Suppression by Plant-Feeding Mites.International journal of molecular sciences · 2018Article
- Jasmonates: News on Occurrence, Biosynthesis, Metabolism and Action of an Ancient Group of Signaling Compounds.International journal of molecular sciences · 2018Review
- Mapping and Functional Analysis of a Maize Silkless MutantFrontiers in plant science · 2018Article
- The Active Jasmonate JA-Ile Regulates a Specific Subset of Plant Jasmonate-Mediated Resistance to Herbivores in Nature.Frontiers in plant science · 2018Article
- Evolution of herbivore-induced early defense signaling was shaped by genome-wide duplications ineLife · 2016Article
- Auxin Is Rapidly Induced by Herbivore Attack and Regulates a Subset of Systemic, Jasmonate-Dependent Defenses.Plant physiology · 2016Article
- Beyond the Canon: Within-Plant and Population-Level Heterogeneity in Jasmonate Signaling Engaged by Plant-Insect Interactions.Plants (Basel, Switzerland) · 2016Review
- Physiological Basis and Transcriptional Profiling of Three Salt-Tolerant Mutant Lines of Rice.Frontiers in plant science · 2016Article
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Authors and funding
4 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
To create a metabolic sink in the jasmonic acid (JA) pathway, we generated transgenic Nicotiana attenuata lines ectopically expressing Arabidopsis (Arabidopsis thaliana) jasmonic acid O-methyltransferase (35S-jmt) and additionally silenced in other lines the N. attenuata methyl jasmonate esterase (35S-jmt/ir-mje) to reduce the deesterification of methyl jasmonate (MeJA). Basal jasmonate levels did not differ between transgenic and wild-type plants; however, after wounding and elicitation with Manduca sexta oral secretions, the bursts of JA, jasmonoyl-isoleucine (JA-Ile), and their metabolites that are normally observed in the lamina, midvein, and petiole of elicited wild-type leaves were largely absent in both transformants but replaced by a burst of endogenous MeJA that accounted for almost half of the total elicited jasmonate pools. In these plants, MeJA became a metabolic sink that affected the jasmonate metabolic network and its spread to systemic leaves, with major effects on 12-oxo-phytodieonic acid, JA, and hydroxy-JA in petioles and on JA-Ile in laminas. Alterations in the size of jasmonate pools were most obvious in systemic tissues, especially petioles. Expression of threonine deaminase and trypsin proteinase inhibitor, two JA-inducible defense genes, was strongly decreased in both transgenic lines without influencing the expression of JA biosynthesis genes that were uncoupled from the wounding and elicitation with M. sexta oral secretions-elicited JA-Ile gradient in elicited leaves. Taken together, this study provides support for a central role of the vasculature in the propagation of jasmonates and new insights into the versatile spatiotemporal characteristics of the jasmonate metabolic network.
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