ArticleJournal of virology2011
Green fluorescent protein reporter system with transcriptional sequence heterogeneity for monitoring the interferon response.
Article in Journal of virology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 26 citations in OpenAlex.
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- Intracellular mono-ADP-ribosyltransferases at the host-virus interphase.Cellular and molecular life sciences : CMLS · 2022Review
- NADFrontiers in molecular biosciences · 2021Review
- Identification of a novel genetic locus underlying tremor and dystonia.Human genomics · 2017Article
- Adult Mouse Liver Contains Two Distinct Populations of Cholangiocytes.Stem cell reports · 2017Article
- Nanopatterned Extracellular Matrices Enable Cell-Based Assays with a Mass Spectrometric Readout.Nano letters · 2017Article
- The conserved macrodomains of the non-structural proteins of Chikungunya virus and other pathogenic positive strand RNA viruses function as mono-ADP-ribosylhydrolases.Scientific reports · 2017Article
- Quantitative Analyses of Core Promoters Enable Precise Engineering of Regulated Gene Expression in Mammalian Cells.ACS synthetic biology · 2016Article
- Human Cytokinome Analysis for Interferon Response.Journal of virology · 2015Article
- Genetic barcoding with fluorescent proteins for multiplexed applications.Journal of visualized experiments : JoVE · 2015Article
- Two- and three-input TALE-based AND logic computation in embryonic stem cells.Nucleic acids research · 2013Article
- Standard fluorescent imaging of live cells is highly genotoxic.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2013Article
- ARTD10 substrate identification on protein microarrays: regulation of GSK3β by mono-ADP-ribosylation.Cell communication and signaling : CCS · 2013Article
- Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10.Nature communications · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
The interferon (IFN) response is initiated by a variety of triggers, including viruses and foreign RNA, and involves several receptors and intracellular mediators. Although there are common cis-acting consensus sequences in the promoters of many genes stimulated during the IFN response, they exhibit core and context heterogeneity that may lead to differential transcriptional activity. We have developed and validated a live cell-based enhanced green fluorescent protein (EGFP) reporter system employing more than a hundred constructs containing multiple viruses and IFN response elements derived from a variety of promoters involved in immunity to viruses. Common and distinct response patterns were observed due to promoter heterogeneity in response to different stimuli, including IFN-α, TLR3-agonist double-stranded RNA, and several viruses. This information should serve as a resource in selecting specific reporters for sensing nonself ligands.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.