Evidence map›Paper›PMID 21752754›Full record

ArticleAmerican journal of obstetrics and gynecology2011

Neonatal morbidity after documented fetal lung maturity in late preterm and early term infants.

Beena D Kamath, Michael P Marcotte, Emily A DeFranco

Abstract read
In one paragraph

Article in American journal of obstetrics and gynecology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Review
  8. A point of care test for the determination of amniotic fluid interleukin-6 and the chemokine CXCL-10/IP-10.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2015
    Article
  9. Neonatal morbidity occurs despite pulmonary maturity prior to 39 weeks gestation.Journal of perinatology : official journal of the California Perinatal Association · 2014
    Article
  10. Review
  11. Amniocentesis for fetal lung maturity: will it become obsolete?Reviews in obstetrics & gynecology · 2013
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Beena D KamathDivision of Neonatology and Pulmonary Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, OH 45229, USA. beena.kamath@cchmc.org
Michael P Marcotte
Emily A DeFranco
Cincinnati Children's Hospital Medical Center · USTriHealth · USUniversity of Cincinnati · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR026314 · NCRR · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E. · 2009 to 2011
$14.3M
Ohio Interdisciplinary Women's Health Career TrainingK12HD051953 · NICHD · UNIVERSITY OF CINCINNATI · PI TSEVAT, JOEL · 2005 to 2014
$4.2M
NCRR NIH HHS UL1 RR026314NCRR NIH HHS UL1-RR026314-01NICHD NIH HHS K12 HD051953
6 · The paper itself

Abstract

objectiveFetal lung maturity often is used as the sole criterion that late preterm infants are ready for postnatal life. We therefore tested the hypothesis that fetal lung maturity testing does not predict the absence of morbidity in late preterm infants. STUDY

designWe performed a retrospective cohort study to examine 152 infants who were born in the late preterm (34 0/7 to 36 6/7 weeks) and early term (37 0/7 to 38 6/7 weeks) periods after mature fetal lung indices and compared them with 262 infants who were born at ≥39 weeks' gestation and who were matched by mode of delivery.

resultsDespite documented fetal lung maturity, infants who were born at <39 weeks had significantly higher rates of neonatal morbidities compared with infants who were born at ≥39 weeks' gestation. After adjustment for significant covariates, we found that infants who were born at <39 weeks' gestation had an increased risk of composite adverse outcome (odds ratio, 3.66; 95% confidence interval, 1.48-9.09; P < .01).

conclusionFetal lung maturity testing is insufficient to determine an infant's readiness for postnatal life.

Indexed as

Fetal Organ MaturityAdultAmniocentesisCohort StudiesGestational AgeHumansInfant, NewbornInfant, Newborn, DiseasesInfant, Premature, DiseasesLungPredictive Value of TestsRetrospective StudiesTerm Birth

Identifiers

PMID21752754
PMCPMC3606819
OpenAlexW2004533867

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.