ReviewCurrent opinion in structural biology2011
Femtosecond nanocrystallography using X-ray lasers for membrane protein structure determination.
Review in Current opinion in structural biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
- High-resolution structure of monomeric photosystem I from Thermosynechococcus vestitus.Photosynthesis research · 2026Article
- Article
- Microcrystal electron diffraction structure of Toll-like receptor 2 TIR-domain-nucleated MyD88 TIR-domain higher-order assembly.Acta crystallographica. Section D, Structural biology · 2024Article
- Ion migration and dark current suppression in quasi-2D perovskite-based X-ray detectors.RSC advances · 2024Article
- Review of serial femtosecond crystallography including the COVID-19 pandemic impact and future outlook.Structure (London, England : 1993) · 2023Review
- Growing and making nano- and microcrystals.Nature protocols · 2023Review
- Serial femtosecond crystallography.Nature reviews. Methods primers · 2022Article
- Imaging conical intersection dynamics during azobenzene photoisomerization by ultrafast X-ray diffraction.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Beyond protein structure determination with MicroED.Current opinion in structural biology · 2020Review
- The cryo-EM method microcrystal electron diffraction (MicroED).Nature methods · 2019Review
- Serial Femtosecond X-Ray Diffraction of HIV-1 Gag MA-IP6 Microcrystals at Ambient Temperature.International journal of molecular sciences · 2019Article
- Sample Delivery Media for Serial Crystallography.International journal of molecular sciences · 2019Review
- Structure of the 30S ribosomal decoding complex at ambient temperature.RNA (New York, N.Y.) · 2018Article
- Monitoring molecular nonadiabatic dynamics with femtosecond X-ray diffraction.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Structure determination from single molecule X-ray scattering with three photons per image.Nature communications · 2018Article
- A Novel Approach to Data Collection for Difficult Structures: Data Management for Large Numbers of Crystals with the BLEND Software.Crystals · 2017Article
- Characterization of Protein Nanocrystals Based on the Reversibility of Crystallization.Crystal growth & design · 2016Article
- Article
- Ultrafast isomerization initiated by X-ray core ionization.Nature communications · 2015Article
- Microfluidic sorting of protein nanocrystals by size for X-ray free-electron laser diffraction.Structural dynamics (Melville, N.Y.) · 2015Article
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2 authors.
Funding
Abstract
The invention of free electron X-ray lasers has opened a new era for membrane protein structure determination with the recent first proof-of-principle of the new concept of femtosecond nanocrystallography. Structure determination is based on thousands of diffraction snapshots that are collected on a fully hydrated stream of nanocrystals. This review provides a summary of the method and describes how femtosecond X-ray crystallography overcomes the radiation-damage problem in X-ray crystallography, avoids the need for growth and freezing of large single crystals while offering a new method for direct digital phase determination by making use of the fully coherent nature of the X-ray beam. We briefly review the possibilities for time-resolved crystallography, and the potential for making 'molecular movies' of membrane proteins at work.
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