ReviewDrug safety2011
Safety considerations in drug treatment of depression in HIV-positive patients: an updated review.
Review in Drug safety, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 31 citations in OpenAlex.
- Article
- The acceptability of antidepressant treatment in people living with HIV in Malawi: A patient perspective.Global public health · 2023Article
- Intersection of Sex and Depression: Pathogenesis, Presentation, and Treatments.Handbook of experimental pharmacology · 2023Article
- Dopaminergic impact of cART and anti-depressants on HIV neuropathogenesis in older adults.Brain research · 2019Review
- Assessment and Management of HIV-Associated Cognitive Impairment: Experience from a Multidisciplinary Memory Service for People Living with HIV.Brain sciences · 2019Article
- Spiritual care may impact mental health and medication adherence in HIV+ populations.HIV/AIDS (Auckland, N.Z.) · 2017Article
- Potential drug interactions in patients given antiretroviral therapy.Revista latino-americana de enfermagem · 2016Article
- Poor CD4 count is a predictor of untreated depression in human immunodeficiency virus-positive African-Americans.World journal of psychiatry · 2016Article
- Cognitive impairment in patients with AIDS - prevalence and severity.HIV/AIDS (Auckland, N.Z.) · 2015Review
- Depression in HIV infected patients: a review.Current psychiatry reports · 2015Review
- Depressive symptoms are increased in the early perimenopausal stage in ethnically diverse human immunodeficiency virus-infected and human immunodeficiency virus-uninfected women.Menopause (New York, N.Y.) · 2012Article
- Role of the Pharmacist in Caring for Patients with HIV/AIDS: Clinical Practice Guidelines.The Canadian journal of hospital pharmacy · 2012Article
- Mental Health in Women Living With HIV: The Unique and Unmet Needs.Journal of the International Association of Providers of AIDS CareReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Major depressive disorder (MDD) is one of the most prevalent illnesses associated with HIV infection, and negatively affects medication adherence, disease progression and mortality in HIV disease. Co-morbid treatment of major depression in HIV disease is the optimal therapeutic approach, but discriminating MDD from normal fluctuations in mood state, personality or physiology is difficult. Definitive diagnosis of MDD is critical for drug safety and for avoiding unnecessary exposure to psychotropic medications. HIV patients respond to antidepressant treatment like the general population, and medication adverse effects and patient adherence are the best predictors of treatment outcome. This review attempts to assist the medical provider with the diagnosis and treatment of MDD in HIV patients. We outline the initial steps in screening and psychiatric referral, the antidepressants that are particularly useful in HIV-infected patients, and the adverse effects and pharmacological strategies for overcoming potential barriers to medication adherence. Potential interactions between the various classes of antidepressants and HIV/antiretroviral therapy, as well as management of HIV medication-related psychiatric adverse effects, are also discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.