Evidence map›Paper›PMID 21751190›Full record

ArticleCancer2012

Early referral to supportive care specialists for symptom burden in lung cancer patients: a comparison of non-Hispanic whites, Hispanics, and non-Hispanic blacks.

Cielito C Reyes-Gibby, Karen O Anderson, Sanjay Shete, Eduardo Bruera, Sriram Yennurajalingam

Registry-linked trialAbstract readComparative Study
In one paragraph

Article in Cancer, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07787806 (A Randomized Controlled, Type 1 Hybrid Effectiveness-implementation Trial Study to Compare the Effectiveness of a Patient-Reported Outcomes), which is not on this map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07787806 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Randomized Controlled, Type 1 Hybrid Effectiveness-implementation Trial Study to Compare the Effectiveness of a Patient-Reported Outcomes (PRO)-Driven Culturally Grounded Supportive Care Navigation in Reducing Healthcare Disparities Among Hispanic/Latinx Patients Receiving Anticancer Therapies

TypeinterventionalSponsorUniversity of California, IrvineRan2026 to 2028Enrolled72ConditionsCancerArmsPatient-Reported Outcomes (PRO)-driven supportive care navigation
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Sociodemographic and Clinical Characteristics Associated With Worst Pain Intensity Among Cancer Patients.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2022
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  18. Racial differences in user experiences and perceived value of electronic symptom monitoring in a cohort of black and white bladder and prostate cancer patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cielito C Reyes-GibbyDepartment of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030-4009, USA. creyes@mdanderson.org
Karen O Anderson
Sanjay Shete
Eduardo Bruera
Sriram Yennurajalingam

Funding

Gene Polymorphism &Treatment-Symptoms in Lung CancerK07CA109043 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI REYES-GIBBY, CIELITO C · 2004 to 2008
$673k
NCI NIH HHS CA109043NCI NIH HHS K07 CA109043
6 · The paper itself

Abstract

backgroundEffective management of symptoms in cancer patients requires early intervention. This study assessed whether the timing of referral to the Supportive Care Center (SCC) and symptom burden outcome varied by race or ethnicity in lung cancer patients who had been seen at a tertiary cancer center.

methodsNon-Hispanic white (n = 752), Hispanic (n = 111), and non-Hispanic black (n = 117) patients with nonsmall cell lung cancer comprised this sample. Data on sociodemographic factors, stage of disease, comorbid conditions, and symptom severity (pain, depressed mood, fatigue) served as potential predictor variables.

resultsWhereas the mean time (15 months; median = 7 months) from initial presentation at the cancer center to referral to the SCC did not vary by race or ethnicity, we found that Hispanics and non-Hispanic blacks had higher symptom burden when they first presented at the cancer center than non-Hispanic whites. Severe pain, depressed mood, and fatigue were significant predictors for early referral (<7 months) of non-Hispanic whites, but only severe fatigue (P <.05) was predictive of early referral for Hispanics and non-Hispanic blacks. Furthermore, while the proportion of non-Hispanic white patients reporting severe pain, depressed mood, and fatigue significantly decreased (P <.001) at first follow-up visit after referral to the SCC; among Hispanics, improvement was only observed for depressed mood. No improvement in any of these symptoms was observed for non-Hispanic blacks.

conclusionsWhereas the timing of referral to supportive services did not vary by race, disparities in symptom burden outcomes persisted. Additional studies are needed to validate our findings.

Indexed as

Healthcare DisparitiesPalliative CareSpecializationAdultAgedBlack PeopleDepressionFatigueFemaleHealth Services AccessibilityHispanic or LatinoHumansLung NeoplasmsMaleMiddle AgedPain

Identifiers

PMID21751190
PMCPMC3193905

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.