ReviewNeurocritical care2011
Seizures and anticonvulsants after aneurysmal subarachnoid hemorrhage.
Review in Neurocritical care, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Neurogenic Fever after Subarachnoid Hemorrhage in Animal Models: A Systematic Review.International journal of molecular sciences · 2023Pooled it
- Antiepileptic drugs for the primary and secondary prevention of seizures after subarachnoid haemorrhage.The Cochrane database of systematic reviews · 2013Pooled it
- A Randomized Trial of Brief Versus Extended Seizure Prophylaxis After Aneurysmal Subarachnoid Hemorrhage.Neurocritical care · 2018Trial
- Article
- Effect of epileptiform discharges and hippocampal volume on cognitive dysfunction following clipping of ruptured aneurysms in the anterior circulation.Frontiers in surgery · 2025Article
- Seizure prophylaxis in pneumococcal meningitis, cohort study.Epilepsia open · 2024Article
- Diagnosis and management of subarachnoid haemorrhage.Nature communications · 2024Review
- Terson Syndrome in Patients with Aneurysmal Subarachnoid Hemorrhage: A 10-Year Single-Center Experience.Neurocritical care · 2023Article
- Fine tuning of neurointensive care in aneurysmal subarachnoid hemorrhage: From one-size-fits-all towards individualized care.World neurosurgery: X · 2023Review
- Clinical Profile and Outcome in Patients with Spontaneous Subarachnoid Hemorrhage from a South Indian Tertiary Centre: A Prospective Observational Study.Asian journal of neurosurgery · 2023Article
- Aneurysmal Subarachnoid Hemorrhage: Review of the Pathophysiology and Management Strategies.Current neurology and neuroscience reports · 2021Review
- New-onset seizures after cranioplasty-a different view on a putatively frequently observed phenomenon.Acta neurochirurgica · 2021Article
- Seizure Prophylaxis in the Immediate Post-Hemorrhagic Period in Patients with Aneurysmal Subarachnoid Hemorrhage.Journal of vascular and interventional neurology · 2017Article
- Outcomes after Early Anticonvulsant Discontinuation in Aneurysmal Subarachnoid Hemorrhage.Journal of vascular medicine & surgery · 2015Article
- High risk for seizures following subarachnoid hemorrhage regardless of referral bias.Neurocritical care · 2014Article
- Lacosamide improves outcome in a murine model of traumatic brain injury.Neurocritical care · 2013Article
- Early seizures after clipping of unruptured aneurysms of the anterior circulation: analysis on consecutive 1,000 cases.Neurosurgical review · 2013Article
- Ultra-early aneurysmal rebleeding and brainstem destruction.Neurocritical care · 2012Article
- Seven questions about stroke and epilepsy.Epilepsy currents · 2012Article
- Blood, sweat, and tears: connecting subarachnoid hemorrhage, systemic inflammation, and nonconvulsive seizures.Epilepsy currentsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Seizures and seizure-like activity may occur in patients experiencing aneurysmal subarachnoid hemorrhage. Treatment of these events with prophylactic antiepileptic drugs remains controversial. An electronic literature search was conducted for English language articles describing the incidence and treatment of seizures after aneurysmal subarachnoid hemorrhage from 1980 to October 2010. A total of 56 articles were included in this review. Seizures often occur at the time of initial presentation or aneurysmal rebleeding before aneurysm treatment. Seizures occur in about 2% of patients after invasive aneurysm treatment, with a higher incidence after surgical clipping compared with endovascular repair. Non-convulsive seizures should be considered in patients with poor neurological status or deterioration. Seizure prophylaxis with antiepileptic drugs is controversial, with limited data available for developing recommendations. While antiepileptic drug use has been linked to worse prognosis, studies have evaluated treatment with almost exclusively phenytoin. When prophylaxis is used, 3-day treatment seems to provide similar seizure prevention with better outcome compared with longer-term treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.