ArticleJournal of clinical research in pediatric endocrinology2011
Cardiac autonomic functions in obese children.
Article in Journal of clinical research in pediatric endocrinology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Pediatric Reference Limits for Holter Monitor Heart Rate Variability Parameters: Defined Using Meta-Analysis.Pediatric cardiology · 2026Article
- Autonomic Function in Obese Children and Adolescents: Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Autonomic dysfunction during the rest-to-exercise transition in obese children.Archivos de cardiologia de Mexico · 2023Article
- Higher frequency of cardiovascular autonomic neuropathy in youth with type 2 compared to type 1 diabetes: Role of cardiometabolic risk factors.Pediatric diabetes · 2022Article
- Anthropometric Determinants of Respiratory Sinus Arrhythmia in Children.International journal of environmental research and public health · 2022Article
- Relationship between heart rate variability and body mass index: A cross-sectional study of preschool children.Preventive medicine reports · 2021Article
- Respiratory Sinus Arrhythmia in Children-Predictable or Random?Frontiers in cardiovascular medicine · 2021Article
- Heart Rate Variability in Children and Adolescents with Cerebral Palsy-A Systematic Literature Review.Journal of clinical medicine · 2020Review
- Longitudinal associations between overweight/obesity and stress biology in low-income children.International journal of obesity (2005) · 2020Article
- Childhood growth patterns and cardiovascular autonomic modulation in midlife: Northern Finland 1966 Birth Cohort Study.International journal of obesity (2005) · 2019Article
- Relationship between Cardiometabolic Parameters and Elevated Resting and Effort Heart Rate in Schoolchildren.Arquivos brasileiros de cardiologia · 2017Article
- Sympathetic Activity Assessed during Exercise Recovery in Young Obese Females.The Journal of pediatrics · 2015Article
- Heart rate variability, adiposity, and physical activity in prepubescent children.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2015Article
- Metabolic syndrome burden in apparently healthy adolescents is adversely associated with cardiac autonomic modulation--Penn State Children Cohort.Metabolism: clinical and experimental · 2015Article
- Salivary alpha amylase diurnal pattern and stress response are associated with body mass index in low-income preschool-aged children.Psychoneuroendocrinology · 2015Article
- Childhood obesity and autonomic dysfunction: risk for cardiac morbidity and mortality.Current treatment options in cardiovascular medicine · 2014Article
- Latino children's body mass index at 2-3.5 years predicts sympathetic nervous system activity at 5 years.Childhood obesity (Print) · 2014Article
- Parasympathetic cardiac activity is associated with cardiorespiratory fitness in overweight and obese adolescents.Pediatric cardiology · 2014Article
- Dysfunction of autonomic nervous system in childhood obesity: a cross-sectional study.PloS one · 2013Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe autonomic nervous system is assumed to have a role in the pathophysiology of obesity. In this study, we evaluated the autonomic system by measuring heart rate variability (HRV) in obese children.
methodsThirty-two obese and 30 healthy children (mean ages: 11.6±2.0 years and 11.0±2.9 years, respectively) were enrolled in the study. Obesity was defined as a body mass index higher than 97th percentile for age- and gender-specific reference values. All participants were free of any disease and none of them was receiving any medication. Twenty-four-hour ambulatory electrocardiographic recordings were obtained and the time-domain and frequency-domain indices of HRV were analyzed. The study group was evaluated with respect to insulin resistance by HOMA-IR values.
resultsA significant decrease in calculated HRV variables was observed in obese children as compared to controls. The HRV alteration was found in both time-domain and frequency-domain parameters. The subgroup analysis of the study group revealed a significant decrease in all investigated HRV parameters in the insulin-resistant obese children compared to the non-insulin-resistant obese ones.
conclusionsOur results indicate that HRV is decreased in obese children, which implies parasympathetic withdrawal and sympathetic predominance. A marked decrease in HRV was observed in insulin-resistant obese children compared to their non-insulin-resistant counterparts. We propose that autonomic imbalance pertaining especially to insulin resistance may be involved in the pathogenesis of obesity in pediatric patients.
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