ArticleClinical ophthalmology (Auckland, N.Z.)2011
Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery.
Article in Clinical ophthalmology (Auckland, N.Z.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- A meta-analysis of topical Ketorolac's effect on surgical site wound healing post-cataract surgery.International wound journal · 2024Pooled it
- Analysis of 24 pro-inflammatory cytokines in aqueous and serum of 94 patients without diabetes.The British journal of ophthalmology · 2025Trial
- Efficacy and tolerability of a gatifloxacin/prednisolone acetate fixed combination for topical prophylaxis and control of inflammation in phacoemulsification: a 20-day-double-blind comparison to its individual components.Clinics (Sao Paulo, Brazil) · 2013Trial
- Loteprednol-Loaded Nanoformulations for Corneal Delivery by Quality-by-Design Concepts: Optimization, Characterization, and Anti-inflammatory Activity.AAPS PharmSciTech · 2023Article
- Discovery of New Heterocyclic/Benzofuran Hybrids as Potential Anti-Inflammatory Agents: Design, Synthesis, and Evaluation of the Inhibitory Activity of Their Related Inflammatory Factors Based on NF-κB and MAPK Signaling Pathways.International journal of molecular sciences · 2023Article
- Metformin attenuated histopathological ocular deteriorations in a streptozotocin-induced hyperglycemic rat model.Naunyn-Schmiedeberg's archives of pharmacology · 2021Article
- Optimization of structures, biochemical properties of ketorolac and its degradation products based on computational studies.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2019Article
- Principles of pharmacology in the eye.British journal of pharmacology · 2017Review
- The safety, pharmacokinetics, and efficacy of intraocular celecoxib.Investigative ophthalmology & visual science · 2014Article
- Intracameral phenylephrine and ketorolac injection (OMS302) for maintenance of intraoperative pupil diameter and reduction of postoperative pain in intraocular lens replacement with phacoemulsification.Clinical ophthalmology (Auckland, N.Z.) · 2014Article
- Non steroidal anti-inflammatory drugs in the prevention of cystoid macular edema after uneventful cataract surgery.Clinical ophthalmology (Auckland, N.Z.) · 2014Article
- Nonsteroidal anti-inflammatory drugs for retinal disease.International journal of inflammation · 2013Article
- A comparative study of various topical nonsteroidal anti-inflammatory drugs to steroid drops for control of post cataract surgery inflammation.Oman journal of ophthalmologyArticle
- Comparing the sedative and analgesic effects of ketorolac and diclofenac eye drops among patients with cataract surgery: A double-blind randomized clinical trial.Oman journal of ophthalmologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this review was to provide a critical appraisal of the literature supporting the efficacy of ophthalmic ketorolac (Acuvail(®)) in the treatment of pain and inflammation after cataract surgery.
methodsLiterature search and expert opinion of the authors.
resultsRecent studies indicate greater intraocular drug levels in the anterior chamber and iris-ciliary body after topical application of Acuvail in comparison with older formulations of ketorolac. A large randomized, multicenter, placebo-controlled study demonstrated significantly less inflammation and pain after cataract surgery using Acuvail.
conclusionAcuvail appears to be effective in reducing post-cataract surgery pain and inflammation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.