ReviewNature reviews. Neurology2011
How might physical activity benefit patients with Parkinson disease?
Review in Nature reviews. Neurology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 110 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Mobile Health Technology to Promote Physical Activity in Persons With Parkinson Disease
Remote Therapeutic Monitoring for Longitudinal Exercise and Self-Efficacy Tracking in Persons With Parkinson's Disease and Multiple Sclerosis.
Effect of Plantar Vibration on Ankle Proprioception in Stroke Patients
Effects of Lumbar Spinal Manipulation on Balance and Fall Risk in Patients With Chronic Stroke: A Randomized Crossover Trial
Who cites it
110 citing papers in PubMed, 9 syntheses or guidelines pooled it, 282 citations in OpenAlex.
- Exercise as a potent antidepressant intervention in Parkinson's disease: a systematic review and meta-analysis of randomised controlled trials.Frontiers in psychology · 2026Pooled it
- Exercise: The key to enhancing sleep quality and physical function in Parkinson's disease? A systematic review and meta-analysis.PloS one · 2025Pooled it
- Physical activity and risk of Parkinson's disease: an updated systematic review and meta-analysis.Journal of neurology · 2024Pooled it
- Relationships between physical activities performed under free-living conditions and non-motor symptoms in people with Parkinson's: A systematic review and meta-analysis.Clinical rehabilitation · 2024Pooled it
- Quality assessment and umbrella review of systematic reviews about dance for people with Parkinson's disease.PloS one · 2024Pooled it
- Pooled it
- Objective Measurement of Walking Activity Using Wearable Technologies in People with Parkinson Disease: A Systematic Review.Sensors (Basel, Switzerland) · 2022Pooled it
- Effect of Physical Activity on Depression in Patients with Parkinson's Disease: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Effectiveness of aerobic and resistance training on the motor symptoms in Parkinson's disease: Systematic review and network meta-analysis.Frontiers in aging neuroscience · 2022Pooled it
- The Effects of Highly Challenging Balance Training in Elderly With Parkinson's Disease: A Randomized Controlled Trial.Neurorehabilitation and neural repair · 2015Trial
- Design of the Park-in-Shape study: a phase II double blind randomized controlled trial evaluating the effects of exercise on motor and non-motor symptoms in Parkinson's disease.BMC neurology · 2015Trial
- Exercise and medication effects on persons with Parkinson disease across the domains of disability: a randomized clinical trial.Journal of neurologic physical therapy : JNPT · 2015Trial
- Promotion of physical activity and fitness in sedentary patients with Parkinson's disease: randomised controlled trial.BMJ (Clinical research ed.) · 2013Trial
- From Static Stability to Dynamic Gait Governance: Differential Effects of Adapted Physical Activity and Tango-Based Therapy on Walking Distance and Plantar Load Redistribution in Parkinson's Disease.Sports (Basel, Switzerland) · 2026Article
- Toward an understanding of real-world mobility in Parkinson's: insights from enhanced contextualisation using GPS-derived location and data-driven modeling of walking speed.Frontiers in aging neuroscience · 2026Article
- Qualitative Assessment of Network Meta-Analyses of Exercise Therapy for Parkinson's Disease: A Scoping Review.Cureus · 2025Review
- Sarcopenia, malnutrition, and fatigue in de Novo Parkinson's disease- support for early rehabilitation.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Interventions for promoting physical activity in people with newly diagnosed Parkinson's disease: scoping review.Systematic reviews · 2025Article
- Review
- Characteristics of the Rest and Activity Patterns in Patients With Mild to Moderate Parkinson's Syndrome.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2025Article
50 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parkinson disease (PD) is a neurodegenerative disorder characterized by progressive motor and nonmotor impairments. These impairments incline many patients towards a sedentary lifestyle, which has many deleterious consequences. Accumulating evidence suggests that patients with PD might benefit from physical activity and exercise in a number of ways, from general improvements in health to disease-specific effects and, potentially, disease-modifying effects (suggested by animal data). Many issues remain to be addressed, including the need to perform clinical trials to demonstrate these presumed benefits of physical activity and exercise in patients with PD. These trials must also address safety issues, such as an increased risk of falls and cardiovascular complications in more-active patients. Identifying ways to induce a sustained behavioral change, using specifically tailored programs that address potential barriers such as depression, apathy and postural instability, may lead to an improved quality of life in individuals with PD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.