ReviewNature reviews. Neurology2011
Multimodal monitoring and neurocritical care bioinformatics.
Review in Nature reviews. Neurology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 120 citations in OpenAlex.
- Intracranial multimodal monitoring in neurocritical care (Neurocore-iMMM): an open, decentralized consensus.Critical care (London, England) · 2024Guideline
- Brain tissue oxygenation, lactate-pyruvate ratio, and cerebrovascular pressure reactivity monitoring in severe traumatic brain injury: systematic review and viewpoint.Neurocritical care · 2014Pooled it
- Unlocking the potential of high-resolution multimodality neuromonitoring for traumatic brain injury management: lessons and insights from cases, events, and patterns.Critical care (London, England) · 2025Review
- A prognostic model for long-term outcome in moderate-severe traumatic brain injury using multimodal neuromonitoring: a retrospective cohort analysis.Frontiers in neurology · 2025Article
- An ultrasensitive multimodal intracranial pressure biotelemetric system enabled by exceptional point and iontronics.Nature communications · 2024Article
- Random forest-based prediction of intracranial hypertension in patients with traumatic brain injury.Intensive care medicine experimental · 2024Article
- The State of the Field of Pediatric Multimodality Neuromonitoring.Neurocritical care · 2024Review
- Predicting outcome after aneurysmal subarachnoid hemorrhage by exploitation of signal complexity: a prospective two-center cohort study.Critical care (London, England) · 2024Article
- Milestones in the history of neurocritical care.Neurological research and practice · 2023Review
- Altered levels of transthyretin in human cerebral microdialysate after subarachnoid haemorrhage using proteomics; a descriptive pilot study.Proteome science · 2023Article
- Multimodal and autoregulation monitoring in the neurointensive care unit.Frontiers in neurology · 2023Review
- Cerebral multimodality monitoring in adult neurocritical care patients with acute brain injury: A narrative review.Frontiers in physiology · 2022Review
- Neurocritical care management of poor-grade subarachnoid hemorrhage: Unjustified nihilism to reasonable optimism.The neuroradiology journal · 2021Review
- Subspace Clustering of Physiological Data From Acute Traumatic Brain Injury Patients: Retrospective Analysis Based on the PROTECT III Trial.JMIR biomedical engineering · 2021Article
- Data Dissemination: Shortening the Long Tail of Traumatic Brain Injury Dark Data.Journal of neurotrauma · 2020Review
- Multimodal neurocritical monitoring.Biomedical journal · 2020Review
- Current Status and Recommendations in Multimodal Neuromonitoring.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2020Article
- Heart Rate Variability in the Perinatal Period: A Critical and Conceptual Review.Frontiers in neuroscience · 2020Review
- Big data in status epilepticus.Epilepsy & behavior : E&B · 2019Review
- Big Data in traumatic brain injury; promise and challenges.Concussion (London, England) · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
Neurocritical care bioinformatics is a new field that focuses on the acquisition, storage and analysis of physiological and other data relevant to the bedside care of patients with acute neurological conditions such as traumatic brain injury or stroke. The main focus of neurocritical care for these conditions relates to prevention, detection and management of secondary brain injury, which relies heavily on monitoring of systemic and cerebral parameters (such as blood-pressure level and intracranial pressure). Advanced neuromonitoring tools also exist that enable measurement of brain tissue oxygen tension, cerebral oxygen utilization, and aerobic metabolism. The ability to analyze these advanced data for real-time clinical care, however, remains intuitive and primitive. Advanced statistical and mathematical tools are now being applied to the large volume of clinical physiological data routinely monitored in neurocritical care with the goal of identifying better markers of brain injury and providing clinicians with improved ability to target specific goals in the management of these patients. This Review provides an introduction to the concepts of multimodal monitoring for secondary brain injury in neurocritical care and outlines initial and future approaches using informatics tools for understanding and applying these data to clinical care.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.