ArticleJournal of endocrinological investigation2012
Prevalence of cardiovascular risk factors in male and female patients with primary hyperparathyroidism.
Article in Journal of endocrinological investigation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07388914 (Aldosterone Variations in Patients With Primary Hyperparathyroidism Before Surgery and in the Year Following Surgery for Parathyroid Disease.), which is not on this map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Aldosterone Variations in Patients With Primary Hyperparathyroidism Before Surgery and in the Year Following Surgery for Parathyroid Disease.
Who cites it
19 citing papers in PubMed, 44 citations in OpenAlex.
- Do Symptoms and Serum Calcium Levels Affect the Results of Surgical Treatment of Primary Hyperparathyroidism?BioMed research international · 2019Trial
- Sex differences in the clinical presentation and complications of primary hyperparathyroidism: insights from a single-center cohort study.Endocrine · 2026Article
- Alterations in serum levels of calcium, vitamin D, phosphorus, and parathyroid hormone in patients with clinically confirmed familial hypercholesterolemia: a cross-sectional study.Annals of medicine and surgery (2012) · 2024Article
- [Gender medicine: endocrine and neuroendocrine diseases : Implications for surgery and perioperative management].Chirurgie (Heidelberg, Germany) · 2024Review
- Stable Incidence and Increasing Prevalence of Primary Hyperparathyroidism in a Population-based Study in Scotland.The Journal of clinical endocrinology and metabolism · 2023Article
- Investigating the risk of metabolic and cardiovascular comorbidities among patients with parathyroid cancer: a nationwide representative cohort study in Taiwan.BMC medicine · 2023Article
- Cardiovascular and metabolic status in patients with primary hyperparathyroidism: a single-center experience.Frontiers in endocrinology · 2023Article
- Clinical phenotypes of primary hyperparathyroidism in hospitalized patients who underwent parathyroidectomy.Endocrine connections · 2021Article
- Parathyroid gland weight is associated with high density lipoprotein levels in patients with primary hyperparathyroidism.Journal of clinical & translational endocrinology · 2020Article
- Symptoms of Primary Hyperparathyroidism in Men and Women: The Same but Different?Visceral medicine · 2020Article
- Primary hyperparathyroidism and hypertension.Gland surgery · 2020Review
- Parathyroidectomy improves cardiovascular risk factors in normocalcemic and hypercalcemic primary hyperparathyroidism.BMC cardiovascular disorders · 2019Article
- Comparison of Initial Clinical Presentations between Primary Hyperparathyroidism Patients from New Brunswick and Changsha.International journal of endocrinology · 2018Article
- The Effect of Hyperparathyroid State on Platelet Functions and Bone Loss.Turkish journal of haematology : official journal of Turkish Society of Haematology · 2016Article
- The Value of the Model and Quantitative Parameters of Contrast-Enhanced Ultrasound in Judging the Severity of SHPT.BioMed research international · 2016Article
- High prevalence of metabolic syndrome in a mestizo group of adult patients with primary hyperparathyroidism (PHPT).BMC endocrine disorders · 2015Article
- Evaluation of left ventricle functions by tissue Doppler, strain, and strain rate echocardiography in patients with primary hyperparathyroidism.Endocrine · 2014Article
- Cardiovascular risk and metabolic syndrome in primary hyperparathyroidism and their correlation to different clinical forms.Endocrine · 2014Article
- Nontraditional manifestations of primary hyperparathyroidism.Journal of clinical densitometry : the official journal of the International Society for Clinical DensitometryReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the prevalence of cardiovascular risk factors in patients with primary hyperparathyroidism (PHPT) and to determine if they are gender specific.
methodsThis was a retrospective case control study. Three hundred and sixty-three men and women with PHPT and 363 age-, sex-, and body mass index (BMI)-matched controls with benign goiter were included in the study. We documented each patient's laboratory results along with the presence of any cardiovascular risk factors. Intra-operatively, the resected parathyroid adenomas were weighed and recorded. The data are expressed as the number of patients in each category and percentage of total patients in that group and the mean±SD.
resultsThe prevalence of obesity, hypertension, hyperlipidemia, Type 2 diabetes, and coronary artery disease (CAD) is higher in PHPT patients compared to the general New Jersey population and age-, sex-, and BMI-matched goiter patients. Male PHPT patients tended to be more obese and were found to have heavier parathyroid adenomas compared to female patients (p<0.05). Additionally, a higher percentage of male PHPT patients were found to have higher rates of CAD (11.5%) and Type 2 diabetes (23.0%) compared to female patients (5.80% and 10.9%, respectively, p<0.05).
conclusionsThere is a higher prevalence of metabolic disorders and CAD in PHPT patients. Male PHPT patients had larger parathyroid adenomas at the time of surgery and had a higher prevalence of obesity, Type 2 diabetes and CAD compared to female PHPT patients.
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