ReviewJournal of endocrinological investigation2011
Diagnosis and treatment of autoimmune hypophysitis: a short review.
Review in Journal of endocrinological investigation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Outcomes of Initial Management Strategies in Patients With Autoimmune Lymphocytic Hypophysitis: A Systematic Review and Meta-analysis.The Journal of clinical endocrinology and metabolism · 2022Pooled it
- Seronegative Hypophysitis Presenting as Unilateral Lateral Rectus Palsy.Annals of Indian Academy of Neurology · 2026Article
- Article
- Central diabetes insipidus with anti-rabphilin-3A antibody positivity causing hypovolemic shock after resection of tumorous lesions in the pelvic cavity.CEN case reports · 2023Article
- Preoperative differentiation of hypophysitis and pituitary adenomas using a novel clinicoradiologic scoring system.Pituitary · 2022Article
- Hypophysitis, the Growing Spectrum of a Rare Pituitary Disease.The Journal of clinical endocrinology and metabolism · 2022Review
- Late-onset hypophysitis after discontinuation of nivolumab treatment for advanced skin melanoma: a case report.BMC endocrine disorders · 2021Article
- Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune checkpoint inhibitor-related adverse events.Journal for immunotherapy of cancer · 2021Article
- Clinical presentation and management of hypophysitis: An observational study of case series.Surgical neurology international · 2021Article
- Hypophysitis: An update on the novel forms, diagnosis and management of disorders of pituitary inflammation.Best practice & research. Clinical endocrinology & metabolism · 2019Review
- Inflammatory Disorders of the Skull Base: a Review.Current neurology and neuroscience reports · 2019Review
- Neuro-radiological features can predict hypopituitarism in primary autoimmune hypophysitis.Pituitary · 2018Article
- Mycophenolate mofetil treatment in a patient with recurrent lymphocytic hypophysitis.BMJ case reports · 2018Article
- Spontaneous pregnancy after full recovery from hypopituitarism caused by lymphocytic hypophysitis.Endocrinology, diabetes & metabolism case reports · 2018Article
- Hypophysitis, Panhypopituitarism, and Hypothalamitis in a Scottish Terrier Dog.Journal of veterinary internal medicine · 2017Article
- Diagnosis and management of tumor-like hypophysitis: A retrospective case series.Oncology letters · 2016Article
- Hypophysitis: Evaluation and Management.Clinical diabetes and endocrinology · 2016Review
- Autoimmune lymphocytic hypophysitis in association with autoimmune eye disease and sequential treatment with infliximab and rituximab.Pituitary · 2015Article
- Primary (autoimmune) hypophysitis: a single centre experience.Pituitary · 2015Article
- Update on hypophysitis and TTF-1 expressing sellar region masses.Brain pathology (Zurich, Switzerland) · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
Medical therapy of autoimmune hypophysitis with immunosuppressive drugs can be effective to induce remission of the disease by treating both pituitary dysfunction and compression symptoms. We describe the case of a 41-yr-old man with autoimmune hypophysitis in whom prednisone therapy induced remission of the disease but was followed by a sudden relapse after withdrawal. A second trial of corticosteroid was started and succeeded in inducing remission of the disease. Eight months after the second withdrawal pituitary function was restored, pituitary mass had disappeared, only partial diabetes insipidus remained unchanged. Review of the literature identified 30 articles, among case reports and case series, reporting a total of 44 cases of autoimmune hypophysitis treated with glucocorticoids and/or azathioprine. Combining all the cases, medical therapy resulted to be effective in reducing the pituitary mass in 84%, in improving anterior pituitary function in 45%, and in restoring posterior pituitary function in 41%. Clinical aspects of autoimmune hypophysitis are discussed and a possible algorithm for the diagnosis and treatment of the disease is proposed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.