Evidence map›Paper›PMID 21750046›Full record

Trial reportAmerican journal of Alzheimer's disease and other dementias2011

Maintaining physical fitness and function in Alzheimer's disease: a pilot study.

Fang Yu, Kay Savik, Jean F Wyman, Ulf G Bronas

Open access · bronzeAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in American journal of Alzheimer's disease and other dementias, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Determination of Aerobic Capacity via Cycle Ergometer Exercise Testing in Alzheimer's Disease.American journal of Alzheimer's disease and other dementias · 2017
    Article
  9. Impact of 6-month aerobic exercise on Alzheimer's symptoms.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2015
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Fang YuSchool of Nursing, University of Minnesota, MN, USA. yuxxx244@umn.edu
Kay Savik
Jean F Wyman
Ulf G Bronas
University of Minnesota · US

Funding

Scholar Development Clinical Research (RMI)K12RR023247 · NCRR · UNIVERSITY OF MINNESOTA TWIN CITIES · PI LUEPKER, RUSSELL V · 2005 to 2009
$13.5M
NCRR NIH HHS K12 RR023247NCRR NIH HHS K12RR023247-04
6 · The paper itself

Abstract

backgroundLittle is known about how aerobic exercise affects physical functioning in persons with Alzheimer's disease (AD).

methodsThis pilot study used a 1-group repeated measures design to examine the feasibility and impact of a 6-month individualized moderate intensity cycling intervention on cardiorespiratory fitness and lower extremity function in 8 participants aged 81.4 ± 3.58. Cardiorespiratory fitness was measured using the shuttle walk and modified YMCA cycle ergometer tests, and lower extremity function was measured using the Short Physical Performance Battery (SPPB) at baseline, 3 months and 6 months.

resultsThe YMCA test showed a significant reduction in heart rate at stage 2 (103.4 vs 90.9 vs 91.6; P = .01), while no significant changes were observed in the shuttle walk and SPPB tests.

conclusionsPersons with AD are able to improve cardiorespiratory conditioning from aerobic exercise. Randomized, controlled trials are needed to confirm these findings. Implications for future research are detailed.

Indexed as

Exercise TherapyActivities of Daily LivingAgedAged, 80 and overAlzheimer DiseaseErgometryExerciseFemaleHeart RateHumansMalePhysical FitnessPilot Projects

Identifiers

PMID21750046
PMCPMC5679098
OpenAlexW2073140291

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.