ArticleAmerican journal of epidemiology2011
Invited commentary: consolidating data harmonization--how to obtain quality and applicability?
Article in American journal of epidemiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03279991 (Neuromed- Integrated Health Life Platform and Biobank), which is not on this map. Cited by 55 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neuromed- Integrated Health Life Platform and Biobank
Who cites it
55 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Genetic background and immune response in paracoccidioidomycosis: A systematic review and meta-analysis of single nucleotide variants.PLoS neglected tropical diseases · 2026Pooled it
- Factors influencing harmonized health data collection, sharing and linkage in Denmark and Switzerland: A systematic review.PloS one · 2019Pooled it
- Risk of acute myocardial infarction with NSAIDs in real world use: bayesian meta-analysis of individual patient data.BMJ (Clinical research ed.) · 2017Pooled it
- Folic acid supplementation use and the MTHFR C677T polymorphism in orofacial clefts etiology: An individual participant data pooled-analysis.Birth defects research. Part A, Clinical and molecular teratology · 2013Pooled it
- An Algorithm for Creating Virtual Controls Using Integrated and Harmonized Longitudinal Data.Evaluation & the health professions · 2018Trial
- Harmonising Depression and Anxiety Measures Across International Cohorts: A Framework Validated Using Measurement Invariance.International journal of methods in psychiatric research · 2026Article
- Unlocking the Power of Data Harmonization in Environmental Health Sciences: A Comprehensive Exploration of Significance, Use Cases, and Recommendations for Standardization Efforts.Environmental health perspectives · 2026Review
- Development and evaluation of wrist- and thigh-worn accelerometer algorithms using self-training machine learning models for classification of activity type and posture: towards device placement-agnostic methods in the ProPASS consortium.The international journal of behavioral nutrition and physical activity · 2026Article
- Bidirectional data harmonization across the multiple chronic disease disparities research consortium: A pipeline description of opportunities and challenges.Journal of biomedical informatics · 2026Article
- Explainable machine learning of PROGRESS-Plus social factors predicts cognitive trajectories after traumatic brain injury.Scientific reports · 2026Article
- Social connection and its prospective association with adolescent internalising and externalising symptoms: an exploratory cross-country study using retrospective harmonisation.Journal of child psychology and psychiatry, and allied disciplines · 2025Article
- Harmonization and integration of data from prospective cohort studies across the Region of the Americas.Revista panamericana de salud publica = Pan American journal of public health · 2025Article
- A natural language processing approach to support biomedical data harmonization: Leveraging large language models.PloS one · 2025Article
- Data Resource Profile: Harmonized health survey data for 240 cities across 11 countries in Latin America: the SALURBAL project.International journal of epidemiology · 2024Article
- Conceptual framework for data harmonisation in mental health using the International Classification of Functioning, Disability and Health: an example with the R2D2-MH consortium.BMJ mental health · 2024Article
- A General Primer for Data Harmonization.Scientific data · 2024Article
- Data cleaning and harmonization of clinical trial data: Medication-assisted treatment for opioid use disorder.PloS one · 2024Article
- Seminar: Scalable Preprocessing Tools for Exposomic Data Analysis.Environmental health perspectives · 2023Article
- Methodological Strategies for Prospective Harmonization of Studies: Application to 10 Distinct Outcomes Studies of Preventive Interventions Targeting Opioid Misuse.Prevention science : the official journal of the Society for Prevention Research · 2023Article
- Unified and pluralistic ideals for data sharing and reuse in biodiversity.Database : the journal of biological databases and curation · 2023Article
Corrections and comments
- Comment on
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is recognized that very large sample sizes capable of providing adequate statistical power are required to properly investigate and understand the role and interaction of genetic, lifestyle, and environmental factors in modulating the risk and progression of chronic diseases. However, very few one-off studies provide access to very large numbers of participants, and the collection of high-quality data necessitates a major investment of resources. The scientific community is thus increasingly engaged in collaborative efforts to facilitate harmonization and synthesis of data across studies. Complementary harmonization approaches may be adopted to support these efforts. In the current issue of the American Journal of Epidemiology, Hamilton et al. (Am J Epidemiol. 2011;174(3):253-260) present the consensus measures for Phenotypes and eXposures (PhenX) Toolkit, which promotes the use of identical data collection tools and procedures to support harmonization across emerging studies. Data synthesis is greatly facilitated by the use of common measures and procedures. However, the "stringent" criteria required by PhenX can limit its utilization. The opportunity to make use of rigorous but more "flexible" harmonization approaches should also be considered.
Indexed as
Identifiers
21749975What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.