Evidence map›Paper›PMID 21749902›Full record

ReviewInternational review of cell and molecular biology2011

New insights into the mechanism of fertilization in nematodes.

Gunasekaran Singaravelu, Andrew Singson

Abstract readReview
In one paragraph

Review in International review of cell and molecular biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. microPublication biology · 2021
    Article
  7. Article
  8. Communication between oocytes and somatic cells regulates volatile pheromone production in Caenorhabditis elegans.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gunasekaran SingaraveluWaksman Institute of Microbiology, Rutgers University, Piscataway, New Jersey, USA.
Andrew Singson

Funding

[RNW] - Gamete Interactions in Caenorhabditis elegansR01HD054681 · NICHD · RUTGERS, THE STATE UNIV OF N.J. · PI ANDREW W. SINGSON · 2008 to 2026
$5.3M
NICHD NIH HHS R01 HD054681NICHD NIH HHS R01HD054681
6 · The paper itself

Abstract

Fertilization results from the fusion of male and female gametes in all sexually reproducing organisms. Much of nematode fertility work was focused on Caenorhabditis elegans and Ascaris suum. The C. elegans hermaphrodite produces a limited number of sperm initially and then commits to the exclusive production of oocytes. The postmeiotic differentiation called spermiogenesis converts sessile spermatids into motile spermatozoa. The motility of spermatozoa depends on dynamic assembly and disassembly of a major sperm protein-based cytoskeleton uniquely found in nematodes. Both self-derived and male-derived spermatozoa are stored in spermatheca, the site of fertilization in hermaphrodites. The oocyte is arrested in meiotic prophase I until a sperm-derived signal relieves the inhibition allowing the meiotic maturation to occur. Oocyte undergoes meiotic maturation, enters into spermatheca, gets fertilized, completes meiosis, and exits into uterus as a zygote. This review focuses on our current understanding of the events around fertilization in nematodes.

Indexed as

AnimalsFertilizationNematodaOocytesSpermatogenesisSperm MotilitySperm-Ovum Interactions

Identifiers

PMID21749902
PMCPMC3273857

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.