ArticleNutrition & metabolism2011
Dietary fructose and risk of metabolic syndrome in adults: Tehran Lipid and Glucose study.
Article in Nutrition & metabolism, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 35 citations in OpenAlex.
- The association between sugars sweetened beverages and glycemic profile among children and youth: A systematic review and dose-response meta-analysis.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Fructose-containing sugars and metabolic risk: a systematic review and meta-analysis.Food & nutrition research · 2025Article
- Dietary simple sugar intake, metabolic indicators, markers of inflammation, and injury among semi-professional football players.Food & nutrition research · 2025Article
- Transcriptomics reveal a molecular signature in the progression of nonalcoholic steatohepatitis and identifies PAI‑1 and MMP‑9 as biomarkers inMolecular medicine reports · 2024Article
- Fructose intake and its association with relative telomere length: an exploratory study among healthy Lebanese adults.Frontiers in nutrition · 2023Article
- A Scoping Review of Epidemiological Studies on Intake of Sugars in Geographically Dispersed Asian Countries: Comparison of Dietary Assessment Methodology.Advances in nutrition (Bethesda, Md.) · 2022Article
- Valorizing Coffee Silverskin Based on Its Phytochemicals and Antidiabetic Potential: From Lab to a Pilot Scale.Foods (Basel, Switzerland) · 2022Article
- Dietary fructose and its association with the metabolic syndrome in Lebanese healthy adults: a cross-sectional study.Diabetology & metabolic syndrome · 2022Article
- Article
- Dietary fructose and risk of metabolic syndrome in Chinese residents aged 45 and above: results from the China National Nutrition and Health Survey.Nutrition journal · 2021Article
- Relationship of added sugars intakes with physiologic parameters in adults: an analysis of national health and nutrition examination survey 2001-2012.AIMS public health · 2020Article
- Carotenoids Inhibit Fructose-Induced Inflammatory Response in Human Endothelial Cells and Monocytes.Mediators of inflammation · 2020Article
- Nutrition and Cardio-Metabolic Risk Factors: Findings from 20 Years of the Tehran Lipid and Glucose Study.International journal of endocrinology and metabolism · 2018Review
- Nutrition and Diabetes, Cardiovascular and Chronic Kidney Diseases: Findings from 20 Years of the Tehran Lipid and Glucose Study.International journal of endocrinology and metabolism · 2018Review
- Longitudinal Associations of High-Fructose Diet with Cardiovascular Events and Potential Risk Factors: Tehran Lipid and Glucose Study.Nutrients · 2017Article
- Familial Aggregation of Metabolic Syndrome With Different Socio-Behavioral Characteristics: The Fourth Phase of Tehran Lipid and Glucose Study.Iranian Red Crescent medical journal · 2016Article
- Nutrient patterns and their relation to general and abdominal obesity in Iranian adults: findings from the SEPAHAN study.European journal of nutrition · 2016Article
- Sugar consumption, metabolic disease and obesity: The state of the controversy.Critical reviews in clinical laboratory sciences · 2016Review
- Sugar-Sweetened Beverage Consumption and Risk of General and Abdominal Obesity in Iranian Adults: Tehran Lipid and Glucose Study.Iranian journal of public health · 2015Article
- Associations of dietary macronutrients with glomerular filtration rate and kidney dysfunction: Tehran lipid and glucose study.Journal of nephrology · 2015Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies have shown that the excessive fructose intake may induce adverse metabolic effects. There is no direct evidence from epidemiological studies to clarify the association between usual amounts of fructose intake and the metabolic syndrome.
objectiveThe aim this study was to determine the association of fructose intake and prevalence of metabolic syndrome (MetS) and its components in Tehranian adults.
methodsThis cross-sectional population based study was conducted on 2537 subjects (45% men) aged 19-70 y, participants of the Tehran Lipid and Glucose Study (2006-2008). Dietary data were collected using a validated 168 item semi-quantitative food frequency questionnaire. Dietary fructose intake was calculated by sum of natural fructose (NF) in fruits and vegetables and added fructose (AF) in commercial foods. MetS was defined according to the modified NCEP ATP III for Iranian adults.
resultsThe mean ages of men and women were 40.5 ± 13.6 and 38.6 ± 12.8 years, respectively. Mean total dietary fructose intakes were 46.5 ± 24.5 (NF: 19.6 ± 10.7 and AF: 26.9 ± 13.9) and 37.3 ± 24.2 g/d (NF: 18.6 ± 10.5 and AF: 18.7 ± 13.6) in men and women, respectively. Compared with those in the lowest quartile of fructose intakes, men and women in the highest quartile, respectively, had 33% (95% CI, 1.15-1.47) and 20% (95% CI, 1.09-1.27) higher risk of the metabolic syndrome; 39% (CI, 1.16-1.63) and 20% (CI, 1.07-1.27) higher risk of abdominal obesity; 11% (CI, 1.02-1.17) and 9% (CI, 1.02-1.14) higher risk of hypertension; and 9% (CI, 1-1.15) and 9% (1.04-1.12) higher risk of impaired fasting glucose.
conclusionHigher consumption of dietary fructose may have adverse metabolic effects.
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