Evidence map›Paper›PMID 21749086›Full record

ArticleOrganic letters2011

Stereoselective synthesis of the eastern quinolizidine portion of himeradine A.

Nathan D Collett, Rich G Carter

Abstract read
In one paragraph

Article in Organic letters, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nathan D CollettDepartment of Chemistry, Oregon State University, Corvallis, Oregon 97331, USA.
Rich G Carter

Funding

Tandem Reactions in Organic SynthesisR01GM063723 · NIGMS · OREGON STATE UNIVERSITY · PI CARTER, RICH GARRETT · 2002 to 2011
$2.1M
NIGMS NIH HHS GM63723NIGMS NIH HHS R01 GM063723
6 · The paper itself

Abstract

The synthesis of the C(15)-C(17)/N(1')-C(11') quinolizidine portion of himeradine A is disclosed. An intramolecular, heteroatom Michael addition was employed to establish the C(6') stereogenic center with high diastereoselectivity. The quinolizidine ring was constructed using microwave-induced cyclization at the N(1')-C(2') position. The C(17) stereogenic center was introduced through a diastereoselective Overman rearrangement.

Indexed as

CyclizationMolecular StructureQuinolizidinesQuinolizinesStereoisomerismhimeradine AQuinolizidinesQuinolizines

Identifiers

PMID21749086
PMCPMC3150458

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.