Evidence map›Paper›PMID 21748745›Full record

ReviewThe Mount Sinai journal of medicine, New York

Delirium in older adults.

Dennis M Popeo

2 registry-linked trialsOpen access · bronzeAbstract readReview
In one paragraph

Review in The Mount Sinai journal of medicine, New York. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05085808 phase4withdrawnnot on this map

Comparison of Trazodone vs Quetiapine vs Placebo for the Treatment of ICU Delirium: A Randomized Controlled Trial (The TraQ Study)

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2028 to 2030Enrolled0ConditionsDelirium, Morality, Quality of Life, PsychArmsTrazodone, Quetiapine, Placebo
NCT05307003 terminatednot on this map

Trazodone vs. Quetiapine for the Treatment of ICU Delirium: A Prospective Observational Pilot Study

TypeobservationalSponsorUniversity of Southern CaliforniaRan2024 to 2024Enrolled10ConditionsDelirium, Delirium of Mixed Origin, Delirium, Sepsis Associated, Delirium in Old AgeArmsTrazodone, Quetiapine
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Delirium in elderly people: a review.Frontiers in neurology · 2012
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Dennis M PopeoMount Sinai School of Medicine, New York, NY, USA. dennis.popeo@mssm.edu
Icahn School of Medicine at Mount Sinai · US

Funding

1/8-Prolonging Remission in Depressed Elderly (PRIDE)U01MH055495 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KELLNER, CHARLES H · 2009 to 2013
$2.0M
NIMH NIH HHS U01 MH055495
6 · The paper itself

Abstract

Delirium is a common neuropsychiatric syndrome in the elderly that can occur in several different settings caused by several different processes. It is common and causes increased morbidity and mortality to those affected. This clinical review discusses the prediction, prevention, diagnosis, and treatment of delirium in the elderly population. Several strategies to predict delirium are noted with the discussion of pharmacological and nonpharmacological trials of prevention and treatment. Diagnosis of delirium, specifically with the use of objective instruments, is discussed, as is the evidence for pharmacological and nonpharmacological treatment strategies. Discussion of the neurobiology and genetic markers for delirium may elucidate further areas for future research.

Indexed as

Geriatric AssessmentAgedAged, 80 and overDeliriumHumans

Identifiers

PMID21748745
PMCPMC3136888
OpenAlexW1993493637

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.