ReviewJournal of cardiovascular translational research2011
Stem cell-based cardiac tissue engineering.
Review in Journal of cardiovascular translational research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Adipose-derived mesenchymal stem cell seeded Atelocollagen scaffolds for cardiac tissue engineering.Journal of materials science. Materials in medicine · 2020Article
- Harnessing the HDAC-histone deacetylase enzymes, inhibitors and how these can be utilised in tissue engineering.International journal of oral science · 2019Review
- Engineered Biomaterials to Enhance Stem Cell-Based Cardiac Tissue Engineering and Therapy.Macromolecular bioscience · 2016Article
- The role of tissue engineering and biomaterials in cardiac regenerative medicine.The Canadian journal of cardiology · 2014Review
- Induced pluripotent stem cells for regenerative medicine.Annual review of biomedical engineering · 2014Review
- Bioreactor for modulation of cardiac microtissue phenotype by combined static stretch and electrical stimulation.Biofabrication · 2014Article
- Article
- Biochemical and physical signal gradients in hydrogels to control stem cell behavior.Advanced materials (Deerfield Beach, Fla.) · 2013Article
- Reconstitution of the myocardium in regenerating newt hearts is preceded by transient deposition of extracellular matrix components.Stem cells and development · 2013Article
- Noninvasive imaging of myocyte apoptosis following application of a stem cell-engineered delivery platform to acutely infarcted myocardium.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2013Article
- Topological and electrical control of cardiac differentiation and assembly.Stem cell research & therapy · 2013Review
- Dissecting the role of human embryonic stem cell-derived mesenchymal cells in human umbilical vein endothelial cell network stabilization in three-dimensional environments.Tissue engineering. Part A · 2013Article
- Embryonic template-based generation and purification of pluripotent stem cell-derived cardiomyocytes for heart repair.Journal of cardiovascular translational research · 2012Review
- Minimally invasive cell-seeded biomaterial systems for injectable/epicardial implantation in ischemic heart disease.International journal of nanomedicine · 2012Review
- Electrical stimulation directs engineered cardiac tissue to an age-matched native phenotype.Journal of tissue engineering · 2012Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Cardiovascular diseases are the leading cause of death worldwide, and cell-based therapies represent a potential cure for patients with cardiac diseases such as myocardial infarction, heart failure, and congenital heart diseases. Towards this goal, cardiac tissue engineering is now being investigated as an approach to support cell-based therapies and enhance their efficacy. This review focuses on the latest research in cardiac tissue engineering based on the use of embryonic, induced pluripotent, or adult stem cells. We describe different strategies such as direct injection of cells and/or biomaterials as well as direct replacement therapies with tissue mimics. In this regard, the latest research has shown promising results demonstrating the improvement of cardiac function with different strategies. It is clear from recent studies that the most important consideration to be addressed by new therapeutic strategies is long-term functional improvement. For this goal to be realized, novel and efficient methods of cell delivery are required that enable high cell retention, followed by electrical integration and mechanical coupling of the injected cells or the engineered tissue to the host myocardium.
Indexed as
Identifiers
21748529What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.