ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2011
Intracranial hemorrhage in children with congenital factor deficiencies.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 33 citations in OpenAlex.
- Management of intracranial hemorrhage in hemophilia A patients.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- Intracranial haemorrhage in children and adults with haemophilia A and B: a literature review of the last 20 years.Blood transfusion = Trasfusione del sangue · 2019Review
- Clinical Characteristics and Prognostic Factors in Hemophiliacs with Intracranial Hemorrhage: A Single-Center, Retrospective Experience.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2016Article
- Fetal intracranial hemorrhage related to maternal autoimmune thrombocytopenic purpura.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2014Article
- Prenatal diagnosis and postnatal outcome of fetal intracranial hemorrhage.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2014Article
- Urgent craniectomy for subdural hematoma in the 8-month-old infant with unrecognized hemophilia B.Korean journal of anesthesiology · 2013Article
- Late-type vitamin K deficiency bleeding: experience from 120 patients.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2012Article
- Women With Congenital Hypofibrinogenemia/Afibrinogenemia: From Birth to Death.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisReview
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8 authors at 2 institutions in 1 country.
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Abstract
backgroundIntracranial hemorrhage (ICH) is a life-threatening situation in childhood. Congenital factor deficiencies (CFD) like hemophilia may cause ICH, and ICH may be the initial presentation in some cases.
methodsFrom 2000 to 2010, 107 children with CFD from Erciyes University, Faculty of Medicine, Department of Pediatric Hematology, were evaluated. The ICH episodes were identified by medical history, general physical examination, detailed neurological examination, and CT or MR scan. The management strategies, surgical intervention, and outcome were noted.
resultsTwenty-one episodes of ICH were seen in 18 patients (16.8%) out of 107 CFD patients. The mean age of the patients was 42.1 months. Fourteen out of 18 patients were male, and four were female. Twelve (57.1%) out of 21 ICH episodes were caused by trauma, and nine (42.9%) were non-trauma related. Epidural hematoma was most frequently observed. All patients survived, but four had decrease in intellectual capacity and motor deficit.
conclusionThe optimal management of ICH in children with CFD depends on immediate recognition and prompt replacement therapy to ensure hemostatic balance with adequate surgical intervention.
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