ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2012
Effectiveness and limitations of autologous osteochondral grafting for the treatment of articular cartilage defects in the knee.
Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 22 citations in OpenAlex.
- Accurate Reporting of Concomitant Procedures Is Highly Variable in Studies Investigating Knee Cartilage Restoration.Cartilage · 2021Article
- Bushenhuoxue Formula Facilitates Articular Cartilage Repair and Attenuates Matrix Degradation by Activation of TGF-Evidence-based complementary and alternative medicine : eCAM · 2018Article
- Influence of basal support and early loading on bone cartilage healing in press-fitted osteochondral autografts.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2014Article
- Early resumption of physical activities leads to inferior clinical outcomes after matrix-based autologous chondrocyte implantation in the knee.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2014Article
- Effect of glutaraldehyde fixation on the frictional response of immature bovine articular cartilage explants.Journal of biomechanics · 2014Article
- Treatment of a lateral tibial plateau osteochondritis dissecans lesion with subchondral injection of calcium phosphate.Arthroscopy techniques · 2013Article
- Weightbearing ovine osteochondral defects heal with inadequate subchondral bone plate restoration: implications regarding osteochondral autograft harvesting.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2012Article
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Authors and funding
5 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the effectiveness and limitations of autologous osteochondral grafting for the treatment of articular cartilage defects in the knee.
methodsThe subjects were 40 patients who had undergone autologous osteochondral grafting. Fifteen knees had cartilage defects combined with anterior cruciate ligament tears (ACL group), 15 knees had cartilage defects combined with osteoarthritis (OA group), and 10 knees had cartilage defects combined with osteochondral dissecans (OCD group). From one to five osteochondral pegs were harvested from the less-weight-bearing periphery of the articular surface of the femoral condyle and grafted to cartilage defects. The clinical results were assessed based on the Lysholm score and radiographic and magnetic resonance imaging (MRI) image assessment.
resultsThe median follow-up duration was 24 months (range from 12 to 41 months). The mean Lysholm score following treatment was improved in all groups. The patients who had cartilage defects combined with OA had a significantly poorer prognosis than did those with cartilage defects combined with ACL or OCD. In the OA group, advanced stage and an alignment abnormality were correlated with poor prognosis. Advanced age was correlated with poor prognosis. Other parameters showed no significant difference in prognosis.
conclusionAutologous osteochondral grafting was found to be an effective technique for treating relatively young patients who had cartilage defects combined with ACL injury or OCD, but this technique showed limited results in treating cartilage defects based on advanced patient age and degenerative changes in the cartilage. LEVEL OF EVIDENCE: Diagnostic studies-investigating a diagnostic test, Level III.
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