Evidence map›Paper›PMID 21747871›Full record

ArticleJournal of allergy2011

Comparison between Airway Responses to High versus Low Molecular Weight Compounds in Occupational Asthma.

D Talini, F Novelli, E Bacci, F L Dente, M De Santis, A Di Franco, L Melosini, B Vagaggini, P L Paggiaro

Open access · hybridAbstract read
In one paragraph

Article in Journal of allergy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Causes and Phenotypes of Work-Related Asthma.International journal of environmental research and public health · 2020
    Review
  2. Article
  3. Article
  4. Review of Diagnostic Challenges in Occupational Asthma.Current allergy and asthma reports · 2017
    Review
  5. Management of work-related asthma: guidelines and challenges.European respiratory review : an official journal of the European Respiratory Society · 2012
    Article
  6. Diagnosis of occupational asthma: an update.Current allergy and asthma reports · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

D TaliniOccupational Health Unit, Prevention Department, Galleria Gerace 14, 56126 Pisa, Italy.
F Novelli
E Bacci
F L Dente
M De Santis
A Di Franco
L Melosini
B Vagaggini
P L Paggiaro
University of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Occupational asthma (OA) is a heterogeneous disease, and the characteristics of the sensitizer responsible for OA may induce different clinical, functional, and biological manifestations. We examined the characteristics of 74 patients with OA induced by low molecular weight compounds (LMWC) or by high molecular weight compounds (HMWC) and diagnosed by specific inhalation challenge (SIC). Patients with OA induced by LMWC had a longer occupational exposure before the beginning of symptoms, a lower sputum eosinophilia, and a higher prevalence of late airway response (LAR), in comparison with patients with OA induced by HMWC. Pulmonary function tended to be poorer and atopy tended to be less frequent in LMWC-induced OA than in HMWC-induced OA. These data confirm and extend previous observations showing that the characteristics of the specific sensitizer inducing OA may determine different clinical, functional, and biological features, probably related to the difference pathogenetic mechanisms underlying these different types of OA.

Identifiers

PMID21747871
PMCPMC3124963
OpenAlexW2138766894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.