ArticleInternational journal of dentistry2011
Effects of orally administered lactoferrin and lactoperoxidase-containing tablets on clinical and bacteriological profiles in chronic periodontitis patients.
Article in International journal of dentistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Trial
- Impact of Modified Lactoperoxidase Systems on Glycolytic Metabolism and Virulence Factors inInternational journal of molecular sciences · 2026Article
- Lactoferrin Solution as a New Natural Photosensitizer in Photodynamic Therapy Against OralMicroorganisms · 2025Article
- Modified Lactoperoxidase System as a Promising Anticaries Agent: In Vitro Studies onInternational journal of molecular sciences · 2023Article
- The role of microbiome-host interactions in the development of Alzheimer´s disease.Frontiers in cellular and infection microbiology · 2023Review
- Oral Diagnostic Methods for the Detection of Periodontal Disease.Diagnostics (Basel, Switzerland) · 2021Article
- Milk lactoperoxidase decreases ID1 and ID3 expression in human oral squamous cell carcinoma cell lines.Scientific reports · 2020Article
- The Significance of Lactoperoxidase System in Oral Health: Application and Efficacy in Oral Hygiene Products.International journal of molecular sciences · 2019Review
- Redox Regulation of Inflammatory Processes Is Enzymatically Controlled.Oxidative medicine and cellular longevity · 2017Review
- Development of a test strip for rapid detection of lactoperoxidase in raw milk.Journal of Zhejiang University. Science. B · 2015Article
- Microbiological effect of essential oils in combination with subgingival ultrasonic instrumentation and mouth rinsing in chronic periodontitis patients.International journal of dentistry · 2013Article
- Role of lactoferrin in periodontal disease: A meta-analytical assessment of its reliability as a biomarker.Medicine internationalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study was undertaken to evaluate the effect of oral administration of lactoferrin (LF) and lactoperoxidase-(LPO-)containing tablet on periodontal condition. Seventy-two individuals with chronic periodontitis were randomly assigned to take either bovine LF and LPO-containing tablets (test group, n = 37) or control tablets (control group, n = 35) every day for 12 weeks. Periodontal parameters and levels of subgingival plaque bacteria, human and bovine LF, and endotoxin in gingival crevicular fluid (GCF) were evaluated at baseline, 1 week, 4 weeks, and 12 weeks. Significant differences were observed in GCF levels of bovine LF between the test and control groups throughout the study (P < .05). However, clinical and bacteriological parameter values proved comparable between the two groups at 1 week to 12 weeks. Therefore, the effect of oral administration of LF and LPO-containing tablets might be weak on periodontal and bacteriological profile in this study.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.