Evidence map›Paper›PMID 21747391›Full record

ReviewNature reviews. Microbiology2011

Leishmaniasis: complexity at the host-pathogen interface.

Paul Kaye, Phillip Scott

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 455 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
455citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

455 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  16. NanoformulatedNanomaterials (Basel, Switzerland) · 2026
    Article
  17. Vector-borne diseases-knowledge maps.EFSA journal. European Food Safety Authority · 2026
    Article
  18. Article
  19. Brain Involvement in Leishmaniasis.Cell biochemistry and function · 2026
    Review
  20. Article

395 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Paul KayeCentre for Immunology and Infection, Department of Biology and Hull York Medical School, University of York, Wentworth Way, UK. paul.kaye@york.ac.uk
Phillip Scott

Funding

Medical Research Council G0400786Medical Research Council G1000230
6 · The paper itself

Abstract

Leishmania is a genus of protozoan parasites that are transmitted by the bite of phlebotomine sandflies and give rise to a range of diseases (collectively known as leishmaniases) that affect over 150 million people worldwide. Cellular immune mechanisms have a major role in the control of infections with all Leishmania spp. However, as discussed in this Review, recent evidence suggests that each host-pathogen combination evokes different solutions to the problems of parasite establishment, survival and persistence. Understanding the extent of this diversity will be increasingly important in ensuring the development of broadly applicable vaccines, drugs and immunotherapeutic interventions.

Indexed as

Host-Pathogen InteractionsImmunity, CellularAnimalsHumansLeishmaniaLeishmaniasisModels, BiologicalPhagosomesPsychodidae

Identifiers

PMID21747391

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.