ArticleAntimicrobial agents and chemotherapy2011
Candida albicans adhesion to and invasion and damage of vaginal epithelial cells: stage-specific inhibition by clotrimazole and bifonazole.
Article in Antimicrobial agents and chemotherapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 56 citations in OpenAlex.
- Vaginal tablets of dequalinium chloride 10 mg versus clotrimazole 100 mg for vaginal candidiasis: a double-blind, randomized study.Archives of gynecology and obstetrics · 2021Trial
- The Biotherapeutic Potential of a Novel ProbioticJournal of fungi (Basel, Switzerland) · 2025Article
- Modulation ofMicroorganisms · 2024Article
- Synergistic anti-virulence efficacy of citral and carvacrol against mixed vaginitis causing Candida albicans and Gardnerella vaginalis: An in vitro and in vivo study.The Journal of antibiotics · 2024Article
- Licochalcone A Protects Vaginal Epithelial Cells Against Candida albicans Infection Via the TLR4/NF-κB Signaling Pathway.Journal of microbiology (Seoul, Korea) · 2024Article
- The Cdc25 and Ras1 Proteins ofJournal of fungi (Basel, Switzerland) · 2023Article
- The Role of Host and Fungal Factors in the Commensal-to-Pathogen Transition ofCurrent clinical microbiology reports · 2023Review
- In vitro infection models to study fungal-host interactions.FEMS microbiology reviews · 2021Review
- Kangbainian Lotion Ameliorates Vulvovaginal Candidiasis in Mice by Inhibiting the Growth of Fluconazole-ResistantFrontiers in pharmacology · 2021Article
- Vulvovaginal Candidiasis: A Current Understanding and Burning Questions.Journal of fungi (Basel, Switzerland) · 2020Review
- Distribution of Pathogenic Yeasts in Different Clinical Samples: Their Identification, Antifungal Susceptibility Pattern, and Cell Invasion Assays.Infection and drug resistance · 2020Article
- Functional divergence of a global regulatory complex governing fungal filamentation.PLoS genetics · 2019Article
- RAFT-Derived Polymethacrylates as a Superior Treatment for Recurrent Vulvovaginal Candidiasis by Targeting Biotic Biofilms and Persister Cells.Frontiers in microbiology · 2019Article
- A tale of two yeasts: Saccharomyces cerevisiae as a therapeutic against candidiasis.Virulence · 2017Article
- Repurposing FDA approved drugs against the human fungal pathogen, Candida albicans.Annals of clinical microbiology and antimicrobials · 2015Article
- Global analysis of fungal morphology exposes mechanisms of host cell escape.Nature communications · 2015Article
- Sulfone derivatives reduce growth, adhesion and aspartic protease SAP2 gene expression.World journal of microbiology & biotechnology · 2014Article
- Attenuation of Candida albicans virulence with focus on disruption of its vacuole functions.Journal of oral microbiology · 2014Review
- Clotrimazole dampens vaginal inflammation and neutrophil infiltration in response to Candida albicans infection.Antimicrobial agents and chemotherapy · 2013Article
- Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clotrimazole and bifonazole are highly effective antifungal agents against mucosal Candida albicans infections. Here we examined the effects of low levels of clotrimazole and bifonazole on the ability of C. albicans to adhere, invade, and damage vaginal epithelial cells. Although adhesion and invasion were not affected, damage was greatly reduced upon azole treatment. This clearly indicates that low levels of azoles influence specific activities of C. albicans during distinct stages of vaginal epithelium infections.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.