ArticleThe Journal of physiology2011
Enhanced high-frequency membrane potential fluctuations control spike output in striatal fast-spiking interneurones in vivo.
Article in The Journal of physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- Synaptic Changes in Pallidostriatal Circuits Observed in the Parkinsonian Model Triggers Abnormal Beta Synchrony with Accurate Spatio-temporal Properties across the Basal Ganglia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Nucleus accumbens local circuit for cue-dependent aversive learning.Cell reports · 2023Article
- Deep brain stimulation in the subthalamic nucleus for Parkinson's disease can restore dynamics of striatal networks.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- A biologically constrained spiking neural network model of the primate basal ganglia with overlapping pathways exhibits action selection.The European journal of neuroscience · 2021Article
- A biophysical model of striatal microcircuits suggests gamma and beta oscillations interleaved at delta/theta frequencies mediate periodicity in motor control.PLoS computational biology · 2020Article
- Frequency-dependent entrainment of striatal fast-spiking interneurons.Journal of neurophysiology · 2019Article
- Excitatory extrinsic afferents to striatal interneurons and interactions with striatal microcircuitry.The European journal of neuroscience · 2019Review
- Coding of self-motion-induced and self-independent visual motion in the rat dorsomedial striatum.PLoS biology · 2018Article
- Cholinergic interneurons in the dorsal and ventral striatum: anatomical and functional considerations in normal and diseased conditions.Annals of the New York Academy of Sciences · 2015Review
- The intralaminar thalamus-an expressway linking visual stimuli to circuits determining agency and action selection.Frontiers in behavioral neuroscience · 2014Review
- Liquid computing on and off the edge of chaos with a striatal microcircuit.Frontiers in computational neuroscience · 2014Article
- Sensitivity to theta-burst timing permits LTP in dorsal striatal adult brain slice.Journal of neurophysiology · 2013Article
- Parvalbumin tunes spike-timing and efferent short-term plasticity in striatal fast spiking interneurons.The Journal of physiology · 2013Article
- Dynamics of action potential firing in electrically connected striatal fast-spiking interneurons.Frontiers in cellular neuroscience · 2013Article
- Relationships between the firing of identified striatal interneurons and spontaneous and driven cortical activities in vivo.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fast-spiking interneurones (FSIs) constitute a prominent part of the inhibitory microcircuitry of the striatum; however, little is known about their recruitment by synaptic inputs in vivo. Here, we report that, in contrast to cholinergic interneurones (CINs), FSIs (n = 9) recorded in urethane-anaesthetized rats exhibit Down-to-Up state transitions very similar to spiny projection neurones (SPNs). Compared to SPNs, the FSI Up state membrane potential was noisier and power spectra exhibited significantly larger power at frequencies in the gamma range (55-95 Hz). The membrane potential exhibited short and steep trajectories preceding spontaneous spike discharge, suggesting that fast input components controlled spike output in FSIs. Spontaneous spike data contained a high proportion (43.6 ± 32.8%) of small inter-spike intervals (ISIs) of <30 ms, setting FSIs clearly apart from SPNs and CINs. Cortical-evoked inputs had slower dynamics in SPNs than FSIs, and repetitive stimulation entrained SPN spike output only if the stimulation was delivered at an intermediate frequency (20 Hz), but not at a high frequency (100 Hz). Pharmacological induction of an activated ECoG state, known to promote rapid FSI spiking, mildly increased the power (by 43 ± 55%, n = 13) at gamma frequencies in the membrane potential of SPNs, but resulted in few small ISIs (<30 ms; 4.3 ± 6.4%, n = 8). The gamma frequency content did not change in CINs (n = 8). These results indicate that FSIs are uniquely responsive to high-frequency input sequences. By controlling the spike output of SPNs, FSIs could serve gating of top-down signals and long-range synchronisation of gamma-oscillations during behaviour.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.