Evidence map›Paper›PMID 21745537›Full record

ReviewBiochimica et biophysica acta2012

S-Nitrosylation signaling regulates cellular protein interactions.

Nadzeya V Marozkina, Benjamin Gaston

Registry-linked trialAbstract readReview
In one paragraph

Review in Biochimica et biophysica acta, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04903535 (Does a Flashlight Used to Detect Pet Biological Fluids on Human Skin and Other Surfaces Increase Gas Phase Nitric Oxide Levels?), which is not on this map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04903535 naenrolling by invitationnot on this mapstarted 2021, after this paper: background citation

Does a Flashlight Used to Detect Pet Biological Fluids on Human Skin and Other Surfaces Increase Gas Phase Nitric Oxide Levels?

TypeinterventionalSponsorIndiana UniversityRan2021 to 2026Enrolled150ConditionsHealthy, UnconsciousArmsAlonefire SV003 10W 365nm UV Flashlight
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 98 citations in OpenAlex.

  1. Article
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  4. Review
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  7. Review
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  11. Review
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  13. NOS2 andProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. S-Nitrosylation: An Emerging Paradigm of Redox Signaling.Antioxidants (Basel, Switzerland) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nadzeya V MarozkinaUniversity of Virginia School of Medicine, Division of Pediatric Respiratory Medicine, PO Box 800386, Charlottesville, VA 22908, USA. nvm6v@virginia.edu
Benjamin Gaston
University of Virginia · US

Funding

S-nitrosothiol signaling in pulmonary epithelial cellsP01HL101871 · NHLBI · UNIVERSITY OF VIRGINIA · PI GASTON, BENJAMIN, LEWIS, STEPHEN JOHN · 2011 to 2015
$8.7M
Airway redox biochemistry as a deteriminant of asthma phenotype during adolescen*U10HL109250 · NHLBI · UNIVERSITY OF VIRGINIA · PI ERZURUM, SERPIL C., GASTON, BENJAMIN · 2011 to 2016
$4.2M
S-NITROSOTHIOL BREAKDOWN BY AIRWAY EPITHELIAL CELLSR01HL059337 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI ZAMAN, KHALEQUZ · 1999 to 2011
$3.0M
NHLBI NIH HHS 1P01HL101871NHLBI NIH HHS 3R01HL59337NHLBI NIH HHS P01 HL101871NHLBI NIH HHS R01 HL059337NHLBI NIH HHS U10 HL109250
6 · The paper itself

Abstract

backgroundS-Nitrosothiols are made by nitric oxide synthases and other metalloproteins. Unlike nitric oxide, S-nitrosothiols are involved in localized, covalent signaling reactions in specific cellular compartments. These reactions are enzymatically regulated. SCOPE: S-Nitrosylation affects interactions involved in virtually every aspect of normal cell biology. This article is part of a Special Issue entitled Regulation of Cellular Processes by S-nitrosylation. MAJOR CONCLUSIONS AND SIGNIFICANCE: S-Nitrosylation is a regulated signaling reaction.

Indexed as

Signal TransductionAnimalsHumansMetalloproteinsNitric OxideNitric Oxide SynthaseNitrosationProteinsProtein Structure, SecondaryProtein TransportS-NitrosothiolsMetalloproteinsNitric OxideNitric Oxide SynthaseProteinsS-Nitrosothiols

Identifiers

PMID21745537
PMCPMC4035225
OpenAlexW2025331065

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.