ArticleAngewandte Chemie (International ed. in English)2011
Aplysqualenol A binds to the light chain of dynein type 1 (DYNLL1).
Article in Angewandte Chemie (International ed. in English), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Lessons in Organic Fluorescent Probe Discovery.Chembiochem : a European journal of chemical biology · 2021Review
- A two-step resin based approach to reveal survivin-selective fluorescent probes.RSC chemical biology · 2021Article
- Bioactive Compounds from Marine Heterobranchs.Marine drugs · 2020Review
- Seselin ameliorates inflammation via targeting Jak2 to suppress the proinflammatory phenotype of macrophages.British journal of pharmacology · 2019Article
- Marine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance.Medicinal research reviews · 2017Review
- Functional chromatographic technique for natural product isolation.Organic & biomolecular chemistry · 2015Article
- Dactyloditerpenol acetate, a new prenylbisabolane-type diterpene from Aplysia dactylomela with significant in vitro anti-neuroinflammatory activity.Bioorganic & medicinal chemistry letters · 2014Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
A bidirectional affinity system has been developed for the identification of cancer-related natural products and their biological targets. Aplysqualenol A is thus selectively identified as a ligand of the dynein light chain. The use of forward and reverse affinity methods suggests that both small-molecule isolation and target identification can be conducted using conventional molecular biological methods.
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Registered trials
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