ArticleFlavour and fragrance journal2011
Genetics of sweet taste preferences.
Article in Flavour and fragrance journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 100 citations in OpenAlex.
- Sweet-liking and sugar supplementation as innovative components in substance use disorder treatment: A systematic review.Journal of psychopharmacology (Oxford, England) · 2025Pooled it
- Artificially sweetened beverage consumption and all-cause and cause-specific mortality: an updated systematic review and dose-response meta-analysis of prospective cohort studies.Nutrition journal · 2024Pooled it
- Strong association between the 12q24 locus and sweet taste preference in the Japanese population revealed by genome-wide meta-analysis.Journal of human genetics · 2020Pooled it
- Exploring the association between sweet liking and treatment response to naltrexone in patients with alcohol use disorder.The international journal of neuropsychopharmacology · 2026Article
- Associations of Individual Beverage Types and Substitution with Dementia Risk: A UK Biobank Cohort Study.The journal of nutrition, health & aging · 2026Article
- Do Not Replace Your Sugar, Simply Eat Less!Diabetes & metabolism journal · 2026Article
- Potential link between tastes preference and digestive system cancer hospitalisations in Fujian Province, China: big data analytics.Public health nutrition · 2025Article
- Choosing sweeteners wisely-nutrigenetic study on childhood obesity.Nutrition & metabolism · 2025Article
- Genetic and Environmental Influences on Sweet Taste Liking and Related Traits: New Insights from Twin Cohorts.Behavior genetics · 2025Article
- Tracking the correlation of mineral intakes among family pairs over nine years: a longitudinal study.BMC nutrition · 2025Article
- Gene variations and sweet taste sensitivity in Zambian adults with and without type 2 diabetes mellitus.PloS one · 2025Article
- Male and female behavioral variability and morphine response in C57BL/6J, DBA/2J, and their BXD progeny following chronic stress exposure.Scientific reports · 2024Article
- A Survey on the Evaluation of Monosodium Glutamate (MSG) Taste in Austria.Foods (Basel, Switzerland) · 2024Article
- Understanding the determinants of sweet taste liking in the African and East Asian ancestry groups in the U.S.-A study protocol.PloS one · 2024Article
- Understanding the Determinants of Sweet Liking in the African and East Asian Ancestry Groups in the U.S. - A Study Protocol.Research square · 2023Article
- Study protocol of the sweet tooth study, randomized controlled trial with partial food provision on the effect of low, regular and high dietary sweetness exposure on sweetness preferences in Dutch adults.BMC public health · 2023Article
- The rs35874116 single nucleotide polymorphism increases sweet intake and the risk of severe early childhood caries: a case-control study.BMC oral health · 2022Article
- Artificial sweeteners and risk of cardiovascular diseases: results from the prospective NutriNet-Santé cohort.BMJ (Clinical research ed.) · 2022Article
- Sensory attributes, dog preference ranking, and oxidation rate evaluation of sorghum-based baked treats supplemented with soluble animal proteins.Journal of animal science · 2022Article
- Exploration of the Impact of Combining Risk Phenotypes on the Likelihood of Alcohol Problems in Young Adults.Alcohol and alcoholism (Oxford, Oxfordshire) · 2022Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 4 countries.
Funding
Abstract
Sweet taste is a powerful factor influencing food acceptance. There is considerable variation in sweet taste perception and preferences within and among species. Although learning and homeostatic mechanisms contribute to this variation in sweet taste, much of it is genetically determined. Recent studies have shown that variation in the T1R genes contributes to within- and between-species differences in sweet taste. In addition, our ongoing studies using the mouse model demonstrate that a significant portion of variation in sweetener preferences depends on genes that are not involved in peripheral taste processing. These genes are likely involved in central mechanisms of sweet taste processing, reward and/or motivation. Genetic variation in sweet taste not only influences food choice and intake, but is also associated with proclivity to drink alcohol. Both peripheral and central mechanisms of sweet taste underlie correlation between sweet-liking and alcohol consumption in animal models and humans. All these data illustrate complex genetics of sweet taste preferences and its impact on human nutrition and health. Identification of genes responsible for within- and between-species variation in sweet taste can provide tools to better control food acceptance in humans and other animals.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.