ArticlePlant physiology2011
The ROOT DETERMINED NODULATION1 gene regulates nodule number in roots of Medicago truncatula and defines a highly conserved, uncharacterized plant gene family.
Article in Plant physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
45 citing papers in PubMed, 107 citations in OpenAlex.
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- Elevated Rates of Molecular Evolution Genome-wide in Mutualist Legumes and Rhizobia.Molecular biology and evolution · 2024Article
- The Defective in Autoregulation (DAR) gene of Medicago truncatula encodes a protein involved in regulating nodulation and arbuscular mycorrhiza.BMC plant biology · 2024Article
- Innovations in functional genomics and molecular breeding of pea: exploring advances and opportunities.aBIOTECH · 2024Review
- Phenotypic characterization and candidate gene analysis of a short kernel and brassinosteroid insensitive mutant from hexaploid oat (Frontiers in plant science · 2024Article
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- CLE peptide signaling in plant-microbe interactions.Frontiers in plant science · 2024Review
- ACurrent issues in molecular biology · 2023Article
- A modified aeroponic system for growing small-seeded legumes and other plants to study root systems.Plant methods · 2023Article
- Photosynthetic Gains in Super-Nodulating Mutants ofPlants (Basel, Switzerland) · 2023Article
- Mutation ofFrontiers in plant science · 2023Article
- Progress in the Self-Regulation System in Legume Nodule Development-AON (Autoregulation of Nodulation).International journal of molecular sciences · 2022Review
- NLP1 reciprocally regulates nitrate inhibition of nodulation through SUNN-CRA2 signaling inPlant communications · 2021Article
- The Regulation of Nodule Number in Legumes Is a Balance of Three Signal Transduction Pathways.International journal of molecular sciences · 2021Review
- Plant ProteinFrontiers in plant science · 2021Review
- Symbiotic Regulatory Genes Controlling Nodule Development inPlants (Basel, Switzerland) · 2020Review
- MIR2111-5 locus and shoot-accumulated mature miR2111 systemically enhance nodulation depending on HAR1 in Lotus japonicus.Nature communications · 2020Article
- The CLE53-SUNN genetic pathway negatively regulates arbuscular mycorrhiza root colonization in Medicago truncatula.Journal of experimental botany · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
The formation of nitrogen-fixing nodules in legumes is tightly controlled by a long-distance signaling system in which nodulating roots signal to shoot tissues to suppress further nodulation. A screen for supernodulating Medicago truncatula mutants defective in this regulatory behavior yielded loss-of-function alleles of a gene designated ROOT DETERMINED NODULATION1 (RDN1). Grafting experiments demonstrated that RDN1 regulatory function occurs in the roots, not the shoots, and is essential for normal nodule number regulation. The RDN1 gene, Medtr5g089520, was identified by genetic mapping, transcript profiling, and phenotypic rescue by expression of the wild-type gene in rdn1 mutants. A mutation in a putative RDN1 ortholog was also identified in the supernodulating nod3 mutant of pea (Pisum sativum). RDN1 is predicted to encode a 357-amino acid protein of unknown function. The RDN1 promoter drives expression in the vascular cylinder, suggesting RDN1 may be involved in initiating, responding to, or transporting vascular signals. RDN1 is a member of a small, uncharacterized, highly conserved gene family unique to green plants, including algae, that we have named the RDN family.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.