Evidence map›Paper›PMID 21741878›Full record

ArticleCurrent opinion in microbiology2011

Mucosal biofilms of Candida albicans.

Shantanu Ganguly, Aaron P Mitchell

Open access · greenAbstract read
In one paragraph

Article in Current opinion in microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 195 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Bioactive Constituents ofDrug design, development and therapy · 2026
    Review
  5. CLEC3A-derived peptides exhibit broad-spectrum activity againstFrontiers in cellular and infection microbiology · 2026
    Article
  6. Article
  7. Optimization of in vitro Biofilm Growth ofIndian journal of microbiology · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Biofilm formation and drug susceptibility of biofilmIranian journal of microbiology · 2024
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Antifungal Activity and Type of Interaction ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  19. Article
  20. Article

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Shantanu GangulyDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213, USA.
Aaron P Mitchell
Carnegie Mellon University · US

Funding

GENETIC CONTROL OF C. ALBICANS BIOFILM FORMATIONR01AI067703 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MITCHELL, AARON P · 2006 to 2014
$3.2M
NIAID NIH HHS R01 AI067703
6 · The paper itself

Abstract

Biofilms are microbial communities that form on surfaces and are embedded in an extracellular matrix. C. albicans forms pathogenic mucosal biofilms that are evoked by changes in host immunity or mucosal ecology. Mucosal surfaces are inhabited by many microbial species; hence these biofilms are polymicrobial. Several recent studies have applied paradigms of biofilm analysis to study mucosal C. albicans infections. These studies reveal that the Bcr1 transcription factor is a master regulator of C. albicans biofilm formation under diverse conditions, though the most relevant Bcr1 target genes can vary with the biofilm niche. An important determinant of mucosal biofilm formation is the interaction with host defenses. Finally, studies of interactions between bacterial species and C. albicans provide insight into the communication mechanisms that endow polymicrobial biofilms with unique properties.

Indexed as

BiofilmsHost-Pathogen InteractionsCandida albicansCandidiasis, OralCandidiasis, VulvovaginalFemaleGene Expression Regulation, FungalGenes, FungalHumansImmunity, InnateMucous MembraneStomatitis, DentureTranscription FactorsTranscription Factors

Identifiers

PMID21741878
PMCPMC3159763
OpenAlexW1994403582

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.