Evidence map›Paper›PMID 21741465›Full record

ReviewBiotechnology advances

Advances in microfluidic PCR for point-of-care infectious disease diagnostics.

Seungkyung Park, Yi Zhang, Shin Lin, Tza-Huei Wang, Samuel Yang

Abstract readReview
In one paragraph

Review in Biotechnology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Biochemically Programmable Isothermal PCR.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  9. Mobile Diagnostic Clinics.ACS sensors · 2024
    Review
  10. Review
  11. Article
  12. Article
  13. Rapid Detection ofJournal of microbiology and biotechnology · 2023
    Article
  14. Article
  15. Engineering Innovative Interfaces for Point-of-Care Diagnostics.Current opinion in colloid & interface science · 2023
    Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Seungkyung ParkDepartment of Emergency Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
Yi Zhang
Shin Lin
Tza-Huei Wang
Samuel Yang

Funding

Vaccine strategy for broad spectrum protection agains non-typhoidal salmonellU54AI057168 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI WHITE, JUDITH M. · 2003 to 2013
$91.5M
NIAID NIH HHS U54 AI057168NIAID NIH HHS U54-AI057168-07
6 · The paper itself

Abstract

Global burdens from existing or emerging infectious diseases emphasize the need for point-of-care (POC) diagnostics to enhance timely recognition and intervention. Molecular approaches based on PCR methods have made significant inroads by improving detection time and accuracy but are still largely hampered by resource-intensive processing in centralized laboratories, thereby precluding their routine bedside- or field-use. Microfluidic technologies have enabled miniaturization of PCR processes onto a chip device with potential benefits including speed, cost, portability, throughput, and automation. In this review, we provide an overview of recent advances in microfluidic PCR technologies and discuss practical issues and perspectives related to implementing them into infectious disease diagnostics.

Indexed as

Microfluidic Analytical TechniquesPoint-of-Care SystemsPolymerase Chain ReactionCommunicable DiseasesDeveloping CountriesGlobal HealthHumans

Identifiers

PMID21741465
PMCPMC3186827

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.