Evidence map›Paper›PMID 21740881›Full record

ReviewHeart rhythm2011

Coronary artery pathophysiology after radiofrequency catheter ablation: review and perspectives.

Adam Castaño, Thomas Crawford, Masatoshi Yamazaki, Uma Mahesh R Avula, Jérôme Kalifa

Abstract readReview
In one paragraph

Review in Heart rhythm, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
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  3. Article
  4. Efficacy, safety, and somatosensory comparison of pulsed-field ablation and thermal ablation: outcomes from a 2-year follow-up.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  5. Coronary Spasm Due to Pulsed Field Ablation: A State-of-the-Art Review.Pacing and clinical electrophysiology : PACE · 2026
    Review
  6. Article
  7. Article
  8. Review
  9. Article
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  14. Electroanatomic visualization of coronary arteries: a case series to elicit safety, feasibility, and diagnostic value in complex ablation procedures.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  15. Complications of catheter ablation for ventricular tachycardia.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Review
  16. Article
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Adam CastañoDepartment of Internal Medicine, Columbia University Medical Center, New York, New York, USA.
Thomas Crawford
Masatoshi Yamazaki
Uma Mahesh R Avula
Jérôme Kalifa
University of Michigan–Ann Arbor · USColumbia University Irving Medical Center · US

Funding

THREE DIMENSIONAL VORTEX LIKE REENTRY IN CORONARY PERFUSED VENTRICULAR WALLP01HL039707 · NHLBI · UPSTATE MEDICAL UNIVERSITY · PI JALIFE, JOSE S · 1990 to 2010
$19.0M
P3: Biophysical Mechanisms in two Arhythmogenic DiseasesP01HL087226 · NHLBI · UPSTATE MEDICAL UNIVERSITY · PI JALIFE, JOSE S · 2007 to 2012
$10.3M
Molecular Mechanisms of Ventricular FibrillationR01HL070074 · NHLBI · UPSTATE MEDICAL UNIVERSITY · PI JALIFE, JOSE S · 2002 to 2007
$1.7M
Mechanical stretch and fibrillation dynamics in the left atriumR01HL087055 · NHLBI · UPSTATE MEDICAL UNIVERSITY · PI KALIFA, JEROME · 2007 to 2011
$1.3M
NHLBI NIH HHS P01 HL039707NHLBI NIH HHS P01 HL087226NHLBI NIH HHS R01 HL070074NHLBI NIH HHS R01 HL087055NHLBI NIH HHS R01-HL087055
6 · The paper itself

Abstract

backgroundRadiofrequency ablation (RFA) has proven to be an effective and safe treatment in patients with ventricular and atrial tachyarrhythmias. Among complications arising after RFA, the incidence of coronary artery (CA) injury is exceedingly low. When CA injury does occur, however, it can be clinically devastating. The proximity of CAs to common ablation sites suggests that the relationship between RFA and CA perfusion pathophysiology is important for optimal lesion formation and safe arrhythmia treatments.

objectiveAlthough others have described the presentation and outcomes of patients with CA injury after ablation, a review that consolidates the mechanisms of CA injury after RFA has yet to be presented in the cardiology literature.

methodsWe conducted an extensive literature search of studies published over the past 30 years that relate the biophysics of RFA with CA perfusion pathophysiology and injury.

resultsWe present a review of the dynamic relationship between RFA and CA perfusion. We describe RFA lesion pathology, mechanisms of CA injury from RFA, and factors that influence lesion formation, such as convective cooling and the shadow effect.

conclusionWe summarize methods to mitigate CA injury after RFA and propose new research avenues to optimize lesion formation and safe arrhythmia treatments when tissue is ablated in the vicinity of CAs.

Indexed as

BurnsCatheter AblationCoronary VesselsHumansTachycardiaTreatment Outcome

Identifiers

PMID21740881
PMCPMC3351104
OpenAlexW2088010289

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.