Evidence map›Paper›PMID 21740415›Full record

ReviewBritish journal of pharmacology2012

Use of inotropes and vasopressor agents in critically ill patients.

Mansoor N Bangash, Ming-Li Kong, Rupert M Pearse

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in British journal of pharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 191 citations in OpenAlex.

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  11. The international, prospective CytOSorbJournal of intensive medicine · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mansoor N BangashWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, UK.
Ming-Li Kong
Rupert M Pearse
William Harvey Research Institute · GB

Funding

Department of Health CS/08/08/17
6 · The paper itself

Abstract

Inotropes and vasopressors are biologically and clinically important compounds that originate from different pharmacological groups and act at some of the most fundamental receptor and signal transduction systems in the body. More than 20 such agents are in common clinical use, yet few reviews of their pharmacology exist outside of physiology and pharmacology textbooks. Despite widespread use in critically ill patients, understanding of the clinical effects of these drugs in pathological states is poor. The purpose of this article is to describe the pharmacology and clinical applications of inotropic and vasopressor agents in critically ill patients.

Indexed as

Critical IllnessAcute Kidney InjuryAnimalsCardiac OutputCardiotonic AgentsCatecholaminesCritical CareHeart ArrestHormonesHumansModels, CardiovascularMyocardial ContractionMyocytes, CardiacSepsisVasoconstrictor AgentsCardiotonic AgentsCatecholaminesHormonesVasoconstrictor Agents

Identifiers

PMID21740415
PMCPMC3413841
OpenAlexW1579077552

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.