ReviewDevelopmental neurobiology2011
Biophysics of substrate interaction: influence on neural motility, differentiation, and repair.
Review in Developmental neurobiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 92 citations in OpenAlex.
- Bidirectional mechanisms and emerging strategies for implantable bioelectronic interfaces.Bioactive materials · 2025Review
- Nanotopographic control of actin waves and growth cone navigation in developing neurons.Frontiers in cell and developmental biology · 2025Article
- Biomechanical Effects of Seizures on Cerebral Dynamics and Brain Stress.Brain sciences · 2024Article
- Biased Random Walk Model of Neuronal Dynamics on Substrates with Periodic Geometrical Patterns.Biomimetics (Basel, Switzerland) · 2023Article
- Neural progenitor cell-derived extracellular matrix as a new platform for neural differentiation of human induced pluripotent stem cells.Biomaterials and biosystems · 2022Article
- Comparison of fractal and grid electrodes for studying the effects of spatial confinement on dissociated retinal neuronal and glial behavior.Scientific reports · 2022Article
- Combined Traction Force-Atomic Force Microscopy Measurements of Neuronal Cells.Biomimetics (Basel, Switzerland) · 2022Article
- Topographic Orientation of Scaffolds for Tissue Regeneration: Recent Advances in Biomaterial Design and Applications.Biomimetics (Basel, Switzerland) · 2022Review
- Physiological Electric Field: A Potential Construction Regulator of Human Brain Organoids.International journal of molecular sciences · 2022Review
- Increased connectivity of hiPSC-derived neural networks in multiphase granular hydrogel scaffolds.Bioactive materials · 2022Article
- Feedback-controlled dynamics of neuronal cells on directional surfaces.Biophysical journal · 2022Article
- Article
- Neuronal Growth and Formation of Neuron Networks on Directional Surfaces.Biomimetics (Basel, Switzerland) · 2021Article
- EngineeringAPL bioengineering · 2021Article
- Understanding, engineering, and modulating the growth of neural networks: An interdisciplinary approach.Biophysics reviews · 2021Review
- The Future of Neuroscience: Flexible and Wireless Implantable Neural Electronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- Article
- Extracellular matrix and biomimetic engineering microenvironment for neuronal differentiation.Neural regeneration research · 2020Review
- A Tale of Two States: Normal and Transformed, With and Without Rigidity Sensing.Annual review of cell and developmental biology · 2019Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The identity and behavior of a cell is shaped by the molecular and mechanical composition of its surroundings. Molecular cues have firmly established roles in guiding both neuronal fate decisions and the migration of cells and axons. However, there is growing evidence that topographical and rigidity cues in the extracellular environment act synergistically with these molecular cues. Like chemical cues, physical factors do not elicit a fixed response, but rather one that depends on the sensory makeup of the cell. Moreover, from developmental studies and the plasticity of neural tissue, it is evident that there is dynamic feedback between physical and chemical factors to produce the final morphology. Here, we focus on our current understanding of how these physical cues shape cellular differentiation and migration, and discuss their relevance to repairing the injured nervous system.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.