ArticleAngewandte Chemie (International ed. in English)2011
Scaffolding catalysts: highly enantioselective desymmetrization reactions.
Article in Angewandte Chemie (International ed. in English), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Rh(II) and Chiral Phosphoric Acid Co-catalyzed Selective O-H Insertions for StereodivergentJournal of the American Chemical Society · 2025Article
- Copper-Catalyzed Asymmetric Sulfonylative Desymmetrization of Glycerol.Molecules (Basel, Switzerland) · 2022Article
- Total Synthesis of (±)-Phyllantidine: Development and Mechanistic Evaluation of a Ring Expansion for Installation of Embedded Nitrogen-Oxygen Bonds.Angewandte Chemie (International ed. in English) · 2020Article
- Site-Selective and StereoselectiveJournal of the American Chemical Society · 2019Article
- Broad-spectrum kinetic resolution of alcohols enabled by Cu-H-catalysed dehydrogenative coupling with hydrosilanes.Nature communications · 2017Article
- Synthesis of 5'-O-DMT-2'-O-TBS Mononucleosides Using an Organic Catalyst.Current protocols in nucleic acid chemistry · 2014Review
- Distal-selective hydroformylation using scaffolding catalysis.Journal of the American Chemical Society · 2014Article
- Resolution of terminal 1,2-diols via silyl transfer.The Journal of organic chemistry · 2013Article
- Practical silyl protection of ribonucleosides.Organic letters · 2013Article
- Site-selective reactions: Exploiting intramolecularity.Nature chemistry · 2013Article
- Catalyst recognition of cis-1,2-diols enables site-selective functionalization of complex molecules.Nature chemistry · 2013Article
- Enantioselective silyl protection of alcohols promoted by a combination of chiral and achiral Lewis basic catalysts.Nature chemistry · 2013Article
- The efficient desymmetrization of glycerol using scaffolding catalysis.Chemical communications (Cambridge, England) · 2013Article
- Site-selective catalysis: toward a regiodivergent resolution of 1,2-diols.Journal of the American Chemical Society · 2012Article
- Catalysis: Temporary intramolecularity.Nature chemistry · 2012Article
- Scaffolding Catalysis: Expanding the Repertoire of Bifunctional Catalysts.Synlett : accounts and rapid communications in synthetic organic chemistry · 2012Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Ex-changing places: a highly enantioselective desymmetrization of 1,2-diols has been developed in which the catalyst utilizes reversible covalent bonding to the substrate to achieve both high selectivity and rate acceleration (see scheme, PMP=pentalmethylpiperidine, TBS=tert-butyldimethylsilyl). Induced intramolecularity is responsible for the enhanced rate, thus allowing the reaction to be performed at room temperature.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.