ArticleDiabetes & metabolism journal2011
Increasing trend in the number of severe hypoglycemia patients in Korea.
Article in Diabetes & metabolism journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Risk factors for hypoglycemia in hospitalized patients with diabetes: a retrospective analysis of electronic medical record data.Frontiers in pharmacology · 2026Article
- Review
- Real-world risk of hypoglycemia-related hospitalization in Japanese patients with type 2 diabetes using SGLT2 inhibitors: a nationwide cohort study.BMJ open diabetes research & care · 2020Article
- Association between BMI and risk of severe hypoglycaemia in type 2 diabetes.Diabetes & metabolism · 2019Article
- Incidence rate and patient characteristics of severe hypoglycemia in treated type 2 diabetes mellitus patients in Japan: Retrospective Diagnosis Procedure Combination database analysis.Journal of diabetes investigation · 2018Article
- A study to evaluate the prevalence of impaired awareness of hypoglycaemia in adults with type 2 diabetes in outpatient clinic in a tertiary care centre in Singapore.Therapeutic advances in endocrinology and metabolism · 2017Article
- Baseline-Corrected QT (QTc) Interval Is Associated with Prolongation of QTc during Severe Hypoglycemia in Patients with Type 2 Diabetes Mellitus.Diabetes & metabolism journal · 2016Article
- 1,5-Anhydro-D-Glucitol Could Reflect Hypoglycemia Risk in Patients with Type 2 Diabetes Receiving Insulin Therapy.Endocrinology and metabolism (Seoul, Korea) · 2016Article
- Severe Hypoglycemia and Cardiovascular or All-Cause Mortality in Patients with Type 2 Diabetes.Diabetes & metabolism journal · 2016Article
- Response: Cardiovascular Disease Predicts Severe Hypoglycemia in Patients with Type 2 Diabetes (Diabetes Metab J 2015;39:498-506).Diabetes & metabolism journal · 2016Article
- Cardiovascular Disease Predicts Severe Hypoglycemia in Patients with Type 2 Diabetes.Diabetes & metabolism journal · 2015Article
- Blood electrolyte disturbances during severe hypoglycemia in Korean patients with type 2 diabetes.The Korean journal of internal medicine · 2015Article
- Intensive individualized reinforcement education is important for the prevention of hypoglycemia in patients with type 2 diabetes.Diabetes & metabolism journal · 2015Article
- 1,5-anhydroglucitol as a useful marker for assessing short-term glycemic excursions in type 1 diabetes.Diabetes & metabolism journal · 2015Article
- Causative anti-diabetic drugs and the underlying clinical factors for hypoglycemia in patients with diabetes.World journal of diabetes · 2015Review
- Hypoglycemia: The neglected complication.Indian journal of endocrinology and metabolism · 2013Review
- Corrected QT Interval Prolongation during Severe Hypoglycemia without Hypokalemia in Patients with Type 2 Diabetes.Diabetes & metabolism journal · 2013Article
- Presence of macroalbuminuria predicts severe hypoglycemia in patients with type 2 diabetes: a 10-year follow-up study.Diabetes care · 2013Article
- Severe hypoglycemia in patients with diabetes.Diabetes & metabolism journal · 2012Article
Corrections and comments
- Erratum issued
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate whether the number of subjects with severe hypoglycemia who are brought to a hospital emergency department is increasing and to identify whether there have been changes in the demographic and clinical characteristics of those subjects.
methodsWe analyzed data from the Emergency Departments of two general hospitals in Seoul, Korea. We included data from all adult subjects with type 2 diabetes who presented to an emergency department with severe hypoglycemia between January 1, 2004 and December 30, 2009.
resultsA total of 740 cases of severe hypoglycemia were identified. The mean subject age was 69±12 years, mean duration of diabetes was 13.8±9.3 years, and 53.2% of subjects were receiving insulin therapy. We observed a sharp rise in the number of cases between 2006 and 2007. Stages 3-5 chronic kidney disease was diagnosed in 31.5% of subjects, and low C-peptide levels (<0.6 ng/mL) were found in 25.5%. The mean subject age, duration of diabetes, HbA1c level, and renal and insulin secretory function values did not change significantly during the study period. The proportion of glimepiride use increased, while use of gliclazide decreased among sulfonylurea users. Use of insulin analogues increased, while use of NPH/RI decreased among insulin users.
conclusionWe identified a sharp increase in the number of subjects with severe hypoglycemia presenting to an emergency room since 2006. The clinical characteristics of these subjects did not change markedly during the study period. Nationwide studies are warranted to further clarify this epidemic of severe hypoglycemia.
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