ReviewNucleus (Austin, Tex.)
Traversing the NPC along the pore membrane: targeting of membrane proteins to the INM.
Review in Nucleus (Austin, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 50 citations in OpenAlex.
- Identification of E3 Ubiquitin Ligase Substrates Using Biotin Ligase-Based Proximity Labeling Approaches.Biomedicines · 2025Review
- Article
- Distribution of Proteins at the Inner Nuclear Membrane Is Regulated by the Asi1 E3 Ligase inGenetics · 2019Article
- In situ architecture of the algal nuclear pore complex.Nature communications · 2018Article
- Mechanisms of ciliary targeting: entering importins and Rabs.Cellular and molecular life sciences : CMLS · 2018Review
- Review
- An improved smaller biotin ligase for BioID proximity labeling.Molecular biology of the cell · 2016Article
- Article
- Identifying Protein-Protein Associations at the Nuclear Envelope with BioID.Methods in molecular biology (Clifton, N.J.) · 2016Article
- Access of torsinA to the inner nuclear membrane is activity dependent and regulated in the endoplasmic reticulum.Journal of cell science · 2015Article
- Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2.Structure (London, England : 1993) · 2015Article
- Live imaging and modeling of inner nuclear membrane targeting reveals its molecular requirements in mammalian cells.The Journal of cell biology · 2015Article
- The Herpes Simplex Virus Protein pUL31 Escorts Nucleocapsids to Sites of Nuclear Egress, a Process Coordinated by Its N-Terminal Domain.PLoS pathogens · 2015Article
- Macromolecular transport between the nucleus and the cytoplasm: Advances in mechanism and emerging links to disease.Biochimica et biophysica acta · 2014Review
- Postage for the messenger: designating routes for nuclear mRNA export.Trends in cell biology · 2013Review
- Mapping of sequences in Pseudorabies virus pUL34 that are required for formation and function of the nuclear egress complex.Journal of virology · 2013Article
- Building a nuclear envelope at the end of mitosis: coordinating membrane reorganization, nuclear pore complex assembly, and chromatin de-condensation.Chromosoma · 2012Review
- Article
- Many mechanisms, one entrance: membrane protein translocation into the nucleus.Cellular and molecular life sciences : CMLS · 2012Review
- Trafficking to uncharted territory of the nuclear envelope.Current opinion in cell biology · 2012Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The inner nuclear membrane (INM) accommodates a specific set of integral membrane proteins many of which interact with chromatin and/or in metazoan cells with the lamina network. The localization of these proteins characterizes this membrane area of the nuclear envelope (NE) despite the fact that the INM forms a membrane continuum with the outer nuclear membrane (ONM) and the remaining endoplasmic reticulum (ER). In fact, the INM can be regarded as a highly specialized membrane subdomain of the ER. How the specific protein composition of the INM is established and maintained and whether this is achieved via a single unifying mechanism is by and large unclear. Recent experiments shed light on some aspects of the process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.