Evidence map›Paper›PMID 21738578›Full record

ArticlePloS one2011

Genomic organization of H2Av containing nucleosomes in Drosophila heterochromatin.

Zhenhai Zhang, B Franklin Pugh

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. In thebioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Histone variants and epigenetics.Cold Spring Harbor perspectives in biology · 2015
    Review
  4. Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Zhenhai ZhangCenter for Comparative Genomics and Bioinformatics, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America.
B Franklin Pugh
Pennsylvania State University · US

Funding

High Resolution Mapping of Function Elements in the Yeast GenomeR01HG004160 · NHGRI · PENNSYLVANIA STATE UNIVERSITY, THE · PI PUGH, B FRANKLIN · 2007 to 2022
$5.3M
High Resolution Mapping of Functional Elements in the Yeast GenomeR56HG004160 · NHGRI · PENNSYLVANIA STATE UNIVERSITY, THE · PI PUGH, B FRANKLIN · 2017 to 2017
$300k
NHGRI NIH HHS HG004160NHGRI NIH HHS R01 HG004160NHGRI NIH HHS R56 HG004160
6 · The paper itself

Abstract

H2Av is a versatile histone variant that plays both positive and negative roles in transcription, DNA repair, and chromatin structure in Drosophila. H2Av, and its broader homolog H2A.Z, tend to be enriched toward 5' ends of genes, and exist in both euchromatin and heterochromatin. Its organization around euchromatin genes and other features have been described in many eukaryotic model organisms. However, less is known about H2Av nucleosome organization in heterochromatin. Here we report the properties and organization of individual H2Av nucleosomes around genes and transposable elements located in Drosophila heterochromatic regions. We compare the similarity and differences with that found in euchromatic regions. Our analyses suggest that nucleosomes are intrinsically positioned on inverted repeats of DNA transposable elements such as those related to the "1360" element, but are not intrinsically positioned on retrotransposon-related elements.

Indexed as

AnimalsDrosophilaGenomeHeterochromatinHistonesInverted Repeat SequencesNucleosomesHeterochromatinHistonesNucleosomes

Identifiers

PMID21738578
PMCPMC3124471
OpenAlexW2012739406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.