Evidence map›Paper›PMID 21738496›Full record

ArticleTopics in current genetics2008

Control of mRNA stability by SAPKs.

Miguel A Rodríguez-Gabriel, Paul Russell

Open access · greenAbstract read
In one paragraph

Article in Topics in current genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Miguel A Rodríguez-GabrielDepto. Microbiologia II. Facultad de Farmacia. Universidad Complutense de Madrid. 28040, Madrid, Spain.
Paul Russell
Scripps Research Institute · USUniversidad Complutense de Madrid · ES

Funding

Yeast Genetics and Stress Response Genes-BiomedicalP42ES010337 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TUKEY, ROBERT H · 2000 to 2022
$69.8M
NIEHS NIH HHS P42 ES010337
6 · The paper itself

Abstract

Control of mRNA turnover is an essential step in the regulation of gene expression in eukaryotes. The concerted action of many enzymes regulates the way each mRNA is degraded. Moreover, the degradation of each mRNA is influenced by the environment surrounding the cell. The conection between the environment and changes in the half-lifes of mRNAs is regulated by the activity of stress activated MAP kinases (SAPKs) and their substrates. Here we will describe some of those mechanisms, and how SAPKs regulate mRNA stability in eukaryotic cells.

Identifiers

PMID21738496
PMCPMC3129863
OpenAlexW1482205154

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.