ArticleClinical journal of the American Society of Nephrology : CJASN2011
Oxalate nephropathy associated with chronic pancreatitis.
Article in Clinical journal of the American Society of Nephrology : CJASN, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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37 citing papers in PubMed, 76 citations in OpenAlex.
- Oxalate Nephropathy in a Patient With Chronic Pancreatitis and Recent Surgery: A Clinical Conundrum.Kidney medicine · 2026Article
- Acute oxalate nephropathy seven years post Roux-en-Y gastric bypass surgery without excessive vitamin C intake: a case report.BMC geriatrics · 2025Article
- Hyperoxaluria: Diagnosis and Treatment.The Urologic clinics of North America · 2025Review
- Oxalate nephropathy precipitated by linaclotide in a high-risk patient.Clinical nephrology. Case studies · 2025Article
- Clinicopathologic Characteristics, Etiologies, and Outcome of Secondary Oxalate Nephropathy.Mayo Clinic proceedings · 2024Article
- Article
- Oxalate Nephropathy and the Mechanism of Oxalate-Induced Kidney Injury.Kidney diseases (Basel, Switzerland) · 2023Review
- Purslane-induced oxalate nephropathy: case report and literature review.BMC nephrology · 2023Review
- Novel Model of Oxalate Diet-Induced Chronic Kidney Disease in Dahl-Salt-Sensitive Rats.International journal of molecular sciences · 2023Article
- A Case of Oxalate Nephropathy Associated With Prolonged Cholecystostomy Tube Placement.Cureus · 2023Article
- The effect and underlying mechanisms of titanium dioxide nanoparticles on glucose homeostasis: A literature review.Journal of applied toxicology : JAT · 2023Review
- Oxalate nephropathy: a review.Clinical kidney journal · 2022Article
- Acute oxalate nephropathy: A potential cause of acute kidney injury in diabetes mellitus-A case series from a single center.Frontiers in medicine · 2022Article
- Detection and localization of calcium oxalate in kidney using synchrotron deep ultraviolet fluorescence microscopy.Journal of synchrotron radiation · 2022Article
- A hidden cause of oxalate nephropathy: a case report.Journal of medical case reports · 2021Article
- Calcium oxalate crystal deposition in the kidney: identification, causes and consequences.Urolithiasis · 2020Review
- Etiologies, Clinical Features, and Outcome of Oxalate Nephropathy.Kidney international reports · 2020Article
- Acute oxalate nephropathy associated withBMJ case reports · 2019Article
- Oxalate nephropathy is a major cause of kidney injury in surgically treated pancreatic adenocarcinoma patients.Clinical kidney journal · 2019Article
- Case report of oxalate nephropathy in a patient with pancreatic metastases from renal carcinoma.BMC cancer · 2019Article
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Authors and funding
10 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesEnteric overabsorption of oxalate may lead to hyperoxaluria and subsequent acute oxalate nephritis (AON). AON related to chronic pancreatitis is a rare and poorly described condition precluding early recognition and treatment. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We collected the clinical characteristics, treatment, and renal outcome of 12 patients with chronic pancreatitis-associated AON followed in four French renal units.
resultsBefore AON, mild to moderate chronic kidney disease was present in all patients, diabetes mellitus in eight (insulin [n = 6]; oral antidiabetic drugs [n = 2]), and known chronic pancreatitis in only eight. At presentation, pancreas imaging showed gland atrophy/heterogeneity, Wirsung duct dilation, calcification, or pseudocyst. Renal findings consisted of rapidly progressive renal failure with tubulointerstitial profile. Acute modification of glomerular filtration preceded the AON (i.e., diarrhea and diuretics). Increase in urinary oxalate excretion was found in all tested patients and hypocalcemia in nine (<1.5 mmol/L in four patients). Renal biopsy showed diffuse crystal deposits, highly suggestive of oxalate crystals, with tubular necrosis and interstitial inflammatory cell infiltrates. Treatment consisted of pancreatic enzyme supplementation, oral calcium intake, and an oxalate-free diet in all patients and renal replacement therapy in five patients. After a median follow-up of 7 months, three of 12 patients reached end-stage renal disease.
conclusionAON is an under-recognized severe crystal-induced renal disease with features of tubulointerstitial nephritis that may occur in patients with a long history of chronic pancreatitis or reveal the pancreatic disease. Extrinsic triggering factors should be prevented.
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