ArticleThe Journal of antimicrobial chemotherapy2011
Is methicillin-resistant Staphylococcus aureus replacing methicillin-susceptible S. aureus?
Article in The Journal of antimicrobial chemotherapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 71 citations in OpenAlex.
- The burden of antimicrobial-resistant bacterial infections: a causal perspective.Nature communications · 2026Review
- spa Typing and Antibiotic Resistance Profiles of Methicillin-Resistant Staphylococcus aureus Isolates From Broilers in Ilam, Iran.Veterinary medicine and science · 2026Article
- Marine Bacteria as a Source of Antibiotics AgainstMarine drugs · 2026Review
- Trends and outcomes in community-onset and hospital-onsetAntimicrobial stewardship & healthcare epidemiology : ASHE · 2024Article
- First comparative genomic characterization of the MSSA ST398 lineage detected in aquaculture and other reservoirs.Frontiers in microbiology · 2023Article
- Methicillin-resistant staphylococcus aureus nosocomial infection has a distinct epidemiological position and acts as a marker for overall hospital-acquired infection trends.Scientific reports · 2022Article
- Burden of Antimicrobial Resistance: Compared to What?Epidemiologic reviews · 2022Article
- Randomized controlled trial of chlorhexidine gluconate, intranasal mupirocin, rifampin, and doxycycline versus chlorhexidine gluconate and intranasal mupirocin alone for the eradication of methicillin-resistantJournal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2021Article
- Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2021Article
- Genomic analysis revealed a novel genotype of methicillin-susceptible Staphylococcus aureus isolated from a fatal sepsis case in dengue patient.Scientific reports · 2021Article
- Healthcare resources attributable to methicillin-resistant Staphylococcus aureus orthopedic surgical site infections.Scientific reports · 2020Article
- The challenges of estimating the human global burden of disease of antimicrobial resistant bacteria.Current opinion in microbiology · 2020Review
- The Role of Amino Acid Substitution in HepT Toward Menaquinone Isoprenoid Chain Length Definition and Lysocin E Sensitivity inFrontiers in microbiology · 2020Article
- Effect of flavonoids on antimicrobial activity of microorganisms present in dental plaque.Heliyon · 2019Article
- Mathematical modelling for antibiotic resistance control policy: do we know enough?BMC infectious diseases · 2019Article
- The Host Immune System Facilitates Disseminated Staphylococcus aureus Disease Due to Phagocytic Attraction to Candida albicans during Coinfection: a Case of Bait and Switch.Infection and immunity · 2019Article
- Quantifying the transmission dynamics of MRSA in the community and healthcare settings in a low-prevalence country.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- A Payer Perspective of the Hospital Inpatient Additional Care Costs of Antimicrobial Resistance in France: A Matched Case-Control Study.Applied health economics and health policy · 2019Article
- Age-Dependent Increase in Incidence of Staphylococcus aureus Bacteremia, Denmark, 2008-2015.Emerging infectious diseases · 2019Article
- Penicillin skin testing in methicillin-sensitive staphylococcus aureus bacteremia: A cost-effectiveness analysis.PloS one · 2019Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
Despite extensive research on the emergence of and treatments for methicillin-resistant Staphylococcus aureus (MRSA), prior studies have not rigorously evaluated the impact of methicillin resistance on the overall incidence of S. aureus infections. Yet, there are direct clinical and research implications of determining whether methicillin-susceptible S. aureus (MSSA) infection rates remain stable in the face of increasing MRSA prevalence or whether MSSA will be replaced over time. A synthesis of prior studies indicates that the emergence of healthcare-associated MRSA (HA-MRSA) and community-associated MRSA (CA-MRSA) has led to an increase in the overall incidence of S. aureus infections, with MRSA principally adding to, rather than replacing, MSSA. However, colonization with CA-MRSA may at least partially replace colonization with MSSA. So far, evidence indicates that MSSA still accounts for many infections. Therefore, eradication of MRSA alone is not sufficient to address the public health burden of S. aureus.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.