Evidence map›Paper›PMID 21737439›Full record

ArticleBioinformatics (Oxford, England)2011

The Cardiac Atlas Project--an imaging database for computational modeling and statistical atlases of the heart.

Carissa G Fonseca, Michael Backhaus, David A Bluemke, Randall D Britten, Jae Do Chung, Brett R Cowan, Ivo D Dinov, J Paul Finn, Peter J Hunter, Alan H Kadish and 7 more

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Society for Cardiovascular Magnetic Resonance (SCMR) expert consensus for CMR imaging endpoints in clinical research: part I - analytical validation and clinical qualification.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2018
    Guideline
  3. Review
  4. Review
  5. Article
  6. 3D cardiac shape analysis with variational point cloud autoencoders for myocardial infarction prediction and virtual heart synthesis.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. MiMICRI: Towards Domain-centered Counterfactual Explanations of Cardiovascular Image Classification Models.Proceedings of the ... Conference on Fairness, Accountability, and Transparency · 2024
    Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. A deep learning approach for fully automated cardiac shape modeling in tetralogy of Fallot.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Article
  19. Article
  20. Article

44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Carissa G FonsecaDepartment of Radiological Sciences, David Geffen School of Medicine, University of California Los Angeles, CA 90095, USA.
Michael Backhaus
David A Bluemke
Randall D Britten
Jae Do Chung
Brett R Cowan
Ivo D Dinov
J Paul Finn
Peter J Hunter
Alan H Kadish
Daniel C Lee
Joao A C Lima
Pau Medrano-Gracia
Kalyanam Shivkumar
Avan Suinesiaputra
Wenchao Tao
Alistair A Young

Funding

Center for Computational Biology (RMI)U54RR021813 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TOGA, ARTHUR W · 2004 to 2010
$25.3M
YALE CENTER FOR THE: LEARNING &ATTENTIONP41RR013642 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BEARER, ELAINE L · 1998 to 2011
$21.9M
PRE-DETERMINE: Biologic Markers and MRI SCD Cohort StudyR01HL091069 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ALBERT, CHRISTINE M · 2008 to 2020
$12.9M
Molecular Biomedical Imaging Laboratory (NIBIB)ZIAEB000072 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI BLUEMKE, DAVID · 2010 to 2017
$5.0M
The Cardiac Atlas Project: Establishment of a Cardiac MRI Database.R01HL087773 · NHLBI · UNIVERSITY OF AUCKLAND · PI YOUNG, ALISTAIR ANDREW · 2008 to 2010
$1.4M
SUBCLINICAL CARDIOVASCULAR DISEASE COORDINATING CENTER-N01HC95159-268095159N01HC095159 · HC · UNIVERSITY OF WASHINGTON · PI KRONMAL, RICHARD A · 1999 to 2006
$304k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--EBCT READINGN01HC095169 · HC · LA BIOMED RES INST/ HARBOR UCLA MED CTR · PI DETRANO, ROBERT · 1999 to 2001
$124k
Molecular Biomedical Imaging Laboratory (CC)ZIACL090019 · CLC · CLINICAL CENTER · PI JONES, ELIZABETH C. · 2010 to 2017
$0k
NCRR NIH HHS P41 RR013642NCRR NIH HHS U54 RR021813NHLBI NIH HHS N01-HC-95159NHLBI NIH HHS N01-HC-95169NHLBI NIH HHS R01HL087773NHLBI NIH HHS R01 HL091069NHLBI NIH HHS R01HL91069
6 · The paper itself

Abstract

motivationIntegrative mathematical and statistical models of cardiac anatomy and physiology can play a vital role in understanding cardiac disease phenotype and planning therapeutic strategies. However, the accuracy and predictive power of such models is dependent upon the breadth and depth of noninvasive imaging datasets. The Cardiac Atlas Project (CAP) has established a large-scale database of cardiac imaging examinations and associated clinical data in order to develop a shareable, web-accessible, structural and functional atlas of the normal and pathological heart for clinical, research and educational purposes. A goal of CAP is to facilitate collaborative statistical analysis of regional heart shape and wall motion and characterize cardiac function among and within population groups.

resultsThree main open-source software components were developed: (i) a database with web-interface; (ii) a modeling client for 3D + time visualization and parametric description of shape and motion; and (iii) open data formats for semantic characterization of models and annotations. The database was implemented using a three-tier architecture utilizing MySQL, JBoss and Dcm4chee, in compliance with the DICOM standard to provide compatibility with existing clinical networks and devices. Parts of Dcm4chee were extended to access image specific attributes as search parameters. To date, approximately 3000 de-identified cardiac imaging examinations are available in the database. All software components developed by the CAP are open source and are freely available under the Mozilla Public License Version 1.1 (http://www.mozilla.org/MPL/MPL-1.1.txt). AVAILABILITY: http://www.cardiacatlas.org CONTACT: a.young@auckland.ac.nz SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Indexed as

Atlases as TopicDatabases, FactualModels, CardiovascularModels, StatisticalAgedAged, 80 and overCardiovascular DiseasesComputational BiologyDiagnostic ImagingFemaleHeartHumansMagnetic Resonance Imaging, CineMaleMiddle AgedMyocardium

Identifiers

PMID21737439
PMCPMC3150036

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.