Evidence map›Paper›PMID 21737438›Full record

ArticleBioinformatics (Oxford, England)2011

Simulating systems genetics data with SysGenSIM.

Andrea Pinna, Nicola Soranzo, Ina Hoeschele, Alberto de la Fuente

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  4. Article
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrea PinnaCRS4 Bioinformatica, 09010 Pula (CA), Italy.
Nicola Soranzo
Ina Hoeschele
Alberto de la Fuente

Funding

Highly multivariate quantitative trait loci mapping in systems geneticsR01HG005254 · NHGRI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI HOESCHELE, INA · 2010 to 2012
$761k
NHGRI NIH HHS 1R01HG005254-01
6 · The paper itself

Abstract

summarySysGenSIM is a software package to simulate Systems Genetics (SG) experiments in model organisms, for the purpose of evaluating and comparing statistical and computational methods and their implementations for analyses of SG data [e.g. methods for expression quantitative trait loci (eQTL) mapping and network inference]. SysGenSIM allows the user to select a variety of network topologies, genetic and kinetic parameters to simulate SG data ( genotyping, gene expression and phenotyping) with large gene networks with thousands of nodes. The software is encoded in MATLAB, and a user-friendly graphical user interface is provided. AVAILABILITY: The open-source software code and user manual can be downloaded at: http://sysgensim.sourceforge.net/ CONTACT: alf@crs4.it.

Indexed as

Gene Regulatory NetworksGenotypeSoftwareComputer SimulationGene ExpressionPhenotype

Identifiers

PMID21737438
PMCPMC3157927

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.